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    Coatomer, alpha subunit [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816678, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Coatomer, alpha subunit
    Primary source
    TAIR:AT2G21390
    Locus tag
    AT2G21390
    See related
    Araport:AT2G21390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F3K23.15; F3K23_15
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (9151940..9156906)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene xylulose kinase-1 Neighboring gene Kinesin motor family protein Neighboring gene uncharacterized protein Neighboring gene SHI-related sequence3 Neighboring gene vacuolar proton ATPase A2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The PII signal transduction protein of Arabidopsis thaliana forms an arginine-regulated complex with plastid N-acetyl glutamate kinase. Chen YM, et al. J Biol Chem, 2006 Mar 3. PMID 16377628
    2. SINAT E3 Ubiquitin Ligases Mediate FREE1 and VPS23A Degradation to Modulate Abscisic Acid Signaling. Xia FN, et al. Plant Cell, 2020 Oct. PMID 32753431, Free PMC Article
    3. The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition. Caillaud MC, et al. PLoS Pathog, 2014 Oct. PMID 25393742, Free PMC Article
    4. Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes. Zhang Y, et al. Plant Cell, 2008 Jun. PMID 18552200, Free PMC Article
    5. The Arabidopsis Proteins AtNHR2A and AtNHR2B Are Multi-Functional Proteins Integrating Plant Immunity With Other Biological Processes. Singh R, et al. Front Plant Sci, 2020. PMID 32194606, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127711.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of COPI vesicle coat IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of Cul4-RING E3 ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Coatomer, alpha subunit
    NP_179734.1
    • Coatomer, alpha subunit; FUNCTIONS IN: structural molecule activity, transporter activity; INVOLVED IN: intracellular protein transport, vesicle-mediated transport, ER to Golgi vesicle-mediated transport; LOCATED IN: COPI vesicle coat, CUL4 RING ubiquitin ligase complex, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), Coatomer, WD associated region (InterPro:IPR006692), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), Coatomer, alpha subunit (InterPro:IPR016391), WD40 repeat, subgroup (InterPro:IPR019781), Quinoprotein amine dehydrogenase, beta chain-like (InterPro:IPR011044), Coatomer, alpha subunit, C-terminal (InterPro:IPR010714); BEST Arabidopsis thaliana protein match is: Coatomer, alpha subunit (TAIR:AT1G62020.1); Has 80927 Blast hits to 31058 proteins in 786 species: Archae - 62; Bacteria - 8761; Metazoa - 33547; Fungi - 17467; Plants - 10193; Viruses - 0; Other Eukaryotes - 10897 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      9151940..9156906
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127711.4 → NP_179734.1  Coatomer, alpha subunit [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179734.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SJT9
      UniProtKB/TrEMBL
      A0A178VW28, A0A5S9X077, A0A654EW13
      Conserved Domains (4) summary
      cd00200
      Location:9 → 317
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:15 → 49
      7WD40; WD40 repeat [structural motif]
      pfam04053
      Location:337 → 769
      Coatomer_WDAD; Coatomer WD associated region
      pfam06957
      Location:816 → 1212
      COPI_C; Coatomer (COPI) alpha subunit C-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJT9.1

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