U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SCY2 SecY protein transport family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817711, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SCY2
    Official Full Name
    SecY protein transport family protein
    Primary source
    TAIR:AT2G31530
    Locus tag
    AT2G31530
    See related
    Araport:AT2G31530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EMB2289; EMBRYO DEFECTIVE 2289; SECY HOMOLOG 2; T9H9.5; T9H9_5
    Summary
    Encodes a component of the thylakoid-localized Sec system involved in the translocation of cytoplasmic proteins into plastid. Loss-of-function mutations result in arrest at the globular stage and embryo lethality.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SCY2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Sequence:
    Chromosome: 2; NC_003071.7 (13427011..13430632)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene neuronal acetylcholine receptor subunit alpha-5 Neighboring gene calcium-dependent protein kinase 24 Neighboring gene IBR domain-containing protein Neighboring gene pseudo Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene signal transducer/transcription protein, putative (DUF1685) Neighboring gene glutathione peroxidase 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Sorting of SEC translocase SCY components to different membranes in chloroplasts. Singhal R, et al. J Exp Bot, 2017 Nov 2. PMID 28992187, Free PMC Article
    2. The Sec2 translocase of the chloroplast inner envelope contains a unique and dedicated SECE2 component. Li Y, et al. Plant J, 2015 Nov. PMID 26406904
    3. Identification of Putative Substrates of SEC2, a Chloroplast Inner Envelope Translocase. Li Y, et al. Plant Physiol, 2017 Apr. PMID 28213560, Free PMC Article
    4. Plastids contain a second sec translocase system with essential functions. Skalitzky CA, et al. Plant Physiol, 2011 Jan. PMID 21051552, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The region of SCY2 that contains transmembrane domains 3 and 4 is necessary for localization to the inner envelope and may serve as a membrane anchor, enhancing the integration of other transmembrane domains via either stop-transfer or post-import mechanisms.
      Title: Sorting of SEC translocase SCY components to different membranes in chloroplasts.
    2. Data show that the SEC2 translocase consisting of SCY2, SECE2, and SECA2 likely integrates a subset of inner envelope membrane proteins.
      Title: Identification of Putative Substrates of SEC2, a Chloroplast Inner Envelope Translocase.
    3. Data indicate that SECE2 plays an essential role in plant growth and development, and specifically interacts with the SCY2 component in vivo.
      Title: The Sec2 translocase of the chloroplast inner envelope contains a unique and dedicated SECE2 component.
    4. SCY2 and SECA2 function in Sec-mediated integration and translocation processes at the inner envelope membrane.
      Title: Plastids contain a second sec translocase system with essential functions.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_128710.7

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within chloroplast organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy NAS
    Non-traceable Author Statement
    more info
    		  
    acts_upstream_of_or_within protein localization to chloroplast IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within thylakoid membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    SecY protein transport family protein
    NP_180711.4
    • EMBRYO DEFECTIVE 2289 (EMB2289); FUNCTIONS IN: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; INVOLVED IN: protein secretion, embryo development ending in seed dormancy; LOCATED IN: chloroplast, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SecY protein (InterPro:IPR002208); BEST Arabidopsis thaliana protein match is: SECY homolog 1 (TAIR:AT2G18710.1); Has 8827 Blast hits to 8825 proteins in 2687 species: Archae - 73; Bacteria - 5355; Metazoa - 4; Fungi - 0; Plants - 96; Viruses - 0; Other Eukaryotes - 3299 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      13427011..13430632
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128710.7 → NP_180711.4  SecY protein transport family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180711.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IQV7, Q8W4F6, Q9SIQ4
      UniProtKB/TrEMBL
      A0A178VNV5, A0A5S9X3H1
      Conserved Domains (2) summary
      PRK09204
      Location:140 → 552
      secY; preprotein translocase subunit SecY; Reviewed
      pfam00344
      Location:207 → 553
      SecY; SecY translocase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4IQV7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools