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    ING2 PHD finger protein-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841881, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ING2
    Official Full Name
    PHD finger protein-like protein
    Primary source
    TAIR:AT1G54390
    Locus tag
    AT1G54390
    See related
    Araport:AT1G54390
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F20D21.22; F20D21_22; INHIBITOR OF GROWTH 2
    Summary
    ING2 encodes a member of the Inhibitor of Growth family of nuclear-localized PhD domain containing homeodomain proteins. Binds to H3K4 di or trimethylated DNA.
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    Genomic context

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    See ING2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    7
    Sequence:
    Chromosome: 1; NC_003070.9 (20304515..20307110, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene spliceosome protein-like protein Neighboring gene ARM repeat superfamily protein Neighboring gene HSP20-like chaperones superfamily protein Neighboring gene dehydrin family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Trithorax group protein Oryza sativa Trithorax1 controls flowering time in rice via interaction with early heading date3. Choi SC, et al. Plant Physiol, 2014 Mar. PMID 24420930, Free PMC Article
    2. Arabidopsis ING and Alfin1-like protein families localize to the nucleus and bind to H3K4me3/2 via plant homeodomain fingers. Lee WY, et al. Plant J, 2009 May. PMID 19154204
    3. The Arabidopsis NuA4 histone acetyltransferase complex is required for chlorophyll biosynthesis and photosynthesis. Zhou JX, et al. J Integr Plant Biol, 2022 Apr. PMID 35043580
    4. The PEAT protein complexes are required for histone deacetylation and heterochromatin silencing. Tan LM, et al. EMBO J, 2018 Oct 1. PMID 30104406, Free PMC Article
    5. AtEAF1 is a potential platform protein for Arabidopsis NuA4 acetyltransferase complex. Bieluszewski T, et al. BMC Plant Biol, 2015 Mar 5. PMID 25849764, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001124016.2
    NM_001160953.1
    NM_001333645.1
    NM_001333646.1
    NM_104317.3
    NM_202296.2
    NM_202297.3
    NM_202298.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables methylated histone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    PHD finger protein-like protein
    NP_001117488.1
    • INHIBITOR OF GROWTH 2 (ING2); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/FYVE/PHD zinc finger superfamily protein (TAIR:AT3G24010.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_001154425.1
    • INHIBITOR OF GROWTH 2 (ING2); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/FYVE/PHD zinc finger superfamily protein (TAIR:AT3G24010.1); Has 1316 Blast hits to 1312 proteins in 191 species: Archae - 0; Bacteria - 0; Metazoa - 731; Fungi - 422; Plants - 94; Viruses - 0; Other Eukaryotes - 69 (source: NCBI BLink).
    NP_564658.2
    • INHIBITOR OF GROWTH 2 (ING2); BEST Arabidopsis thaliana protein match is: RING/FYVE/PHD zinc finger superfamily protein (TAIR:AT3G24010.1); Has 1029 Blast hits to 893 proteins in 166 species: Archae - 2; Bacteria - 0; Metazoa - 705; Fungi - 173; Plants - 97; Viruses - 0; Other Eukaryotes - 52 (source: NCBI BLink).
    NP_974025.1
    • INHIBITOR OF GROWTH 2 (ING2); BEST Arabidopsis thaliana protein match is: RING/FYVE/PHD zinc finger superfamily protein (TAIR:AT3G24010.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_974026.1
    • INHIBITOR OF GROWTH 2 (ING2); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/FYVE/PHD zinc finger superfamily protein (TAIR:AT3G24010.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_974027.1
    • INHIBITOR OF GROWTH 2 (ING2); CONTAINS InterPro DOMAIN/s: Zinc finger, PHD-type (InterPro:IPR001965), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: RING/FYVE/PHD zinc finger superfamily protein (TAIR:AT3G24010.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20304515..20307110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202298.3 → NP_974027.1  PHD finger protein-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974027.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H615, Q8L631, Q9SLJ4
      UniProtKB/TrEMBL
      A0A178WC19, A0A5S9WM91, A0A7G2E0N6
      Conserved Domains (2) summary
      COG5034
      Location:10 → 256
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd17015
      Location:17 → 122
      ING_plant; Inhibitor of growth (ING) domain of plant inhibitor of growth proteins

    2. NM_202297.3 → NP_974026.1  PHD finger protein-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974026.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H615, Q8L631, Q9SLJ4
      UniProtKB/TrEMBL
      A0A178WC19, A0A5S9WM91, A0A7G2E0N6
      Conserved Domains (2) summary
      COG5034
      Location:10 → 256
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd17015
      Location:17 → 122
      ING_plant; Inhibitor of growth (ING) domain of plant inhibitor of growth proteins

    3. NM_001124016.2 → NP_001117488.1  PHD finger protein-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001117488.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HWW5
      Conserved Domains (2) summary
      COG5034
      Location:56 → 236
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cl28919
      Location:17 → 102
      ING; Inhibitor of growth (ING) domain family

    4. NM_104317.3 → NP_564658.2  PHD finger protein-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564658.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B3H615
      Conserved Domains (2) summary
      pfam12998
      Location:9 → 122
      ING; Inhibitor of growth proteins N-terminal histone-binding
      cl22851
      Location:208 → 226
      PHD_SF; PHD finger superfamily

    5. NM_001333645.1 → NP_001320514.1  PHD finger protein-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HWW5
      Conserved Domains (2) summary
      COG5034
      Location:56 → 236
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cl28919
      Location:17 → 102
      ING; Inhibitor of growth (ING) domain family

    6. NM_202296.2 → NP_974025.1  PHD finger protein-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974025.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HWW1
      Conserved Domains (2) summary
      pfam12998
      Location:9 → 122
      ING; Inhibitor of growth proteins N-terminal histone-binding
      cl22851
      Location:208 → 226
      PHD_SF; PHD finger superfamily

    7. NM_001160953.1 → NP_001154425.1  PHD finger protein-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001154425.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8LE83
      Conserved Domains (3) summary
      COG5034
      Location:1 → 175
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cd15505
      Location:127 → 174
      PHD_ING; PHD finger found in the inhibitor of growth (ING) protein family
      pfam12998
      Location:3 → 41
      ING; Inhibitor of growth proteins N-terminal histone-binding

    8. NM_001333646.1 → NP_001320513.1  PHD finger protein-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HWW5
      Conserved Domains (2) summary
      COG5034
      Location:56 → 236
      TNG2; Chromatin remodeling protein, contains PhD zinc finger [Chromatin structure and dynamics]
      cl28919
      Location:17 → 102
      ING; Inhibitor of growth (ING) domain family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B3H615.1

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