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    CRR28 Tetratricopeptide repeat (TPR)-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842263, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRR28
    Official Full Name
    Tetratricopeptide repeat (TPR)-like superfamily protein
    Primary source
    TAIR:AT1G59720
    Locus tag
    AT1G59720
    See related
    Araport:AT1G59720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CHLORORESPIRATORY REDUCTION28; F23H11.3; F23H11_3
    Summary
    Pentatricopeptide Repeat Protein containing the DYW motif. Required for editing of multiple plastid transcripts. Endonuclease activity.
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    Genomic context

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    See CRR28 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (21939752..21941784, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene glutathione S-transferase TAU 16 Neighboring gene actin cross-linking protein (DUF569) Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pentatricopeptide repeat proteins with the DYW motif have distinct molecular functions in RNA editing and RNA cleavage in Arabidopsis chloroplasts. Okuda K, et al. Plant Cell, 2009 Jan. PMID 19182104, Free PMC Article
    2. An RNA recognition motif-containing protein is required for plastid RNA editing in Arabidopsis and maize. Sun T, et al. Proc Natl Acad Sci U S A, 2013 Mar 19. PMID 23487777, Free PMC Article
    3. Quantitative analysis of motifs contributing to the interaction between PLS-subfamily members and their target RNA sequences in plastid RNA editing. Okuda K, et al. Plant J, 2014 Dec. PMID 25279799
    4. A zinc finger motif-containing protein is essential for chloroplast RNA editing. Sun T, et al. PLoS Genet, 2015 Mar. PMID 25768119, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CRR28, CRR21, OTP85 and OTP80 act as site-recognition factors for plastid RNA editing.
      Title: Quantitative analysis of motifs contributing to the interaction between PLS-subfamily members and their target RNA sequences in plastid RNA editing.
    2. DYW proteins CRR22 and CRR28 are involved in multiple RNA editing events. Replacement of the DYW motifs by that of CRR2 blocks the editing activity of both proteins.
      Title: Pentatricopeptide repeat proteins with the DYW motif have distinct molecular functions in RNA editing and RNA cleavage in Arabidopsis chloroplasts.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • At1g59720_Arabidopsis_lyrata_ssp._lyrata_CAN1 (e-PCR)
    • At1g59720_Arabidopsis_lyrata_ssp._petraea_GER10 (e-PCR)

    Homology

    NM_104664.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA modification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Tetratricopeptide repeat (TPR)-like superfamily protein
    NP_176180.1
    • CHLORORESPIRATORY REDUCTION28 (CRR28); CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT4G21065.1); Has 31527 Blast hits to 13136 proteins in 216 species: Archae - 0; Bacteria - 0; Metazoa - 40; Fungi - 37; Plants - 31097; Viruses - 0; Other Eukaryotes - 353 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      21939752..21941784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104664.2 → NP_176180.1  Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176180.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WQW5, Q9LQ42, Q9XIF6
      UniProtKB/TrEMBL
      A0A178W310, A0A5S9WSF6, A0A654EL65
      Conserved Domains (2) summary
      PLN03081
      Location:102 → 638
      PLN03081; pentatricopeptide (PPR) repeat-containing protein; Provisional
      sd00004
      Location:219 → 246
      PPR; PPR repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WQW5.2

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