U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PHS1 poor homologous synapsis 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837614, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    PHS1
    Official Full Name
    poor homologous synapsis 1
    Primary source
    TAIR:AT1G10710
    Locus tag
    AT1G10710
    See related
    Araport:AT1G10710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    POOR HOMOLOGOUS SYNAPSIS 1; T16B5.15
    Summary
    Computational predictions suggested the presence of a small cysteine-rich protein beginning in intron 9 (Silverstein 2007), but subsequent analysis revealed that this region contains a tenth exon for the At1g10710 gene. PHS1 regulates recombination and pairing of homologous chromosomes during meiotic prophase by controlling transport of RAD50 from cytoplasm to the nucleus.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See PHS1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Sequence:
    Chromosome: 1; NC_003070.9 (3558358..3560705)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene phosphoribosyl pyrophosphate (PRPP) synthase 3 Neighboring gene miscRNA Neighboring gene EMBRYO SURROUNDING FACTOR-like protein Neighboring gene EMBRYO SURROUNDING FACTOR-like protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. PHS1 regulates meiotic recombination and homologous chromosome pairing by controlling the transport of RAD50 to the nucleus. Ronceret A, et al. Proc Natl Acad Sci U S A, 2009 Nov 24. PMID 19918061, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    NM_001084039.1
    NM_001331923.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in homologous chromosome pairing at meiosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    poor homologous synapsis 1
    NP_001077508.1
    • POOR HOMOLOGOUS SYNAPSIS 1 (PHS1); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G10717.1); Has 43 Blast hits to 42 proteins in 8 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 43; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).
    NP_001318974.1
    • POOR HOMOLOGOUS SYNAPSIS 1 (PHS1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: zygotene, synapsis, leptotene; LOCATED IN: cytoplasm; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 6 growth stages; Has 27 Blast hits to 26 proteins in 8 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 27; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3558358..3560705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001084039.1 → NP_001077508.1  poor homologous synapsis 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077508.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4I5W5, Q45GQ7, Q5BQ17, Q9SAD1
      UniProtKB/TrEMBL
      A0A5S9TP67, A0A654EA68
      Conserved Domains (1) summary
      cl17171
      Location:89 → 153
      PH-like; Pleckstrin homology-like domain

    2. NM_001331923.1 → NP_001318974.1  poor homologous synapsis 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654EA68
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q45GQ7.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.