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    HAF01 HAC13 protein (HAC13) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 840169, updated on 18-Sep-2024

    Summary

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    Official Symbol
    HAF01
    Official Full Name
    HAC13 protein (HAC13)
    Primary source
    TAIR:AT1G32750
    Locus tag
    AT1G32750
    See related
    Araport:AT1G32750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6N18.13; F6N18_13; GTD01; GTD1; HAC13; HAF1; HISTONE ACETYLTRANSFERASE OF THE CBP FAMILY 13; HISTONE ACETYLTRANSFERASE OF THE CBP FAMILY 13; HISTONE ACETYLTRANSFERASE OF THE TAFII250 FAMILY 1; TAF1; TBP-ASSOCIATED FACTOR 1
    Summary
    This gene is predicted to encode a histone acetyltransferase. Five lines with RNAi constructs directed against HAF1 grow normally and can produce root calli, but have defects in agrobacterium-mediated transformation.
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    Genomic context

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    See HAF01 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    22
    Sequence:
    Chromosome: 1; NC_003070.9 (11846247..11856765, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Cytochrome C oxidase polypeptide VIB family protein Neighboring gene electron carrier/iron ion-binding protein Neighboring gene SBP (S-ribonuclease binding protein) family protein Neighboring gene ncRNA Neighboring gene Glutaredoxin family protein Neighboring gene Cysteine-rich protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis TAF1 is an MRE11-interacting protein required for resistance to genotoxic stress and viability of the male gametophyte. Waterworth WM, et al. Plant J, 2015 Nov. PMID 26358508, Free PMC Article
    2. Yeast two-hybrid map of Arabidopsis TFIID. Lawit SJ, et al. Plant Mol Biol, 2007 May. PMID 17340043
    3. RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation. Crane YM, et al. Proc Natl Acad Sci U S A, 2007 Sep 18. PMID 17827277, Free PMC Article
    4. Analysis of histone acetyltransferase and histone deacetylase families of Arabidopsis thaliana suggests functional diversification of chromatin modification among multicellular eukaryotes. Pandey R, et al. Nucleic Acids Res, 2002 Dec 1. PMID 12466527, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_103009.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-mediated transformation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    HAC13 protein (HAC13)
    NP_174552.1
    • HAF01; FUNCTIONS IN: histone acetyltransferase activity, DNA binding; INVOLVED IN: DNA mediated transformation; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TAFII-230 TBP-binding (InterPro:IPR009067), Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955), Bromodomain, conserved site (InterPro:IPR018359), Bromodomain (InterPro:IPR001487); BEST Arabidopsis thaliana protein match is: histone acetyltransferase of the TAFII250 family 2 (TAIR:AT3G19040.1); Has 22854 Blast hits to 14376 proteins in 1001 species: Archae - 24; Bacteria - 596; Metazoa - 11292; Fungi - 2677; Plants - 2799; Viruses - 159; Other Eukaryotes - 5307 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      11846247..11856765 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_103009.4 → NP_174552.1  HAC13 protein (HAC13) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_174552.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LRK9, Q9LPI9
      UniProtKB/TrEMBL
      A0A5S9WIK6, A0A654EES7
      Conserved Domains (6) summary
      cd04369
      Location:1806 → 1901
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      smart00213
      Location:661 → 730
      UBQ; Ubiquitin homologues
      pfam09247
      Location:27 → 64
      TBP-binding; TATA box-binding protein binding
      pfam12157
      Location:578 → 1146
      DUF3591; Protein of unknown function (DUF3591)
      pfam15288
      Location:1399 → 1432
      zf-CCHC_6; Zinc knuckle
      cl00155
      Location:661 → 733
      UBQ; Ubiquitin-like proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LRK9.1

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