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    ORA59 octadecanoid-responsive AP2/ERF 59 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837125, updated on 22-Oct-2024

    Summary

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    Official Symbol
    ORA59
    Official Full Name
    octadecanoid-responsive AP2/ERF 59
    Primary source
    TAIR:AT1G06160
    Locus tag
    AT1G06160
    See related
    Araport:AT1G06160
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F9P14.2; F9P14_2; octadecanoid-responsive Arabidopsis AP2/ERF 59
    Summary
    encodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
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    Genomic context

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    See ORA59 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    1
    Sequence:
    Chromosome: 1; NC_003070.9 (1882907..1883992)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene basic helix loop helix (bHLH) DNA-binding superfamily protein Neighboring gene uncharacterized protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The AP2/ERF transcription factor ORA59 regulates ethylene-induced phytoalexin synthesis through modulation of an acyltransferase gene expression. Huang LJ, et al. J Cell Physiol, 2024 Oct. PMID 36538653
    2. The transcription factor ORA59 exhibits dual DNA binding specificity that differentially regulates ethylene- and jasmonic acid-induced genes in plant immunity. Yang YN, et al. Plant Physiol, 2021 Dec 4. PMID 34890461, Free PMC Article
    3. Jasmonic acid/ethylene signaling coordinates hydroxycinnamic acid amides biosynthesis through ORA59 transcription factor. Li J, et al. Plant J, 2018 Aug. PMID 29752755
    4. Salicylic acid suppresses jasmonic acid signaling downstream of SCFCOI1-JAZ by targeting GCC promoter motifs via transcription factor ORA59. Van der Does D, et al. Plant Cell, 2013 Feb. PMID 23435661, Free PMC Article
    5. The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense. Pré M, et al. Plant Physiol, 2008 Jul. PMID 18467450, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The AP2/ERF transcription factor ORA59 regulates ethylene-induced phytoalexin synthesis through modulation of an acyltransferase gene expression.
      Title: The AP2/ERF transcription factor ORA59 regulates ethylene-induced phytoalexin synthesis through modulation of an acyltransferase gene expression.
    2. The transcription factor ORA59 exhibits dual DNA binding specificity that differentially regulates ethylene- and jasmonic acid-induced genes in plant immunity.
      Title: The transcription factor ORA59 exhibits dual DNA binding specificity that differentially regulates ethylene- and jasmonic acid-induced genes in plant immunity.
    3. Arabidopsis CURLY LEAF functions in leaf immunity against fungal pathogens by concomitantly repressing SEPALLATA3 and activating ORA59.
      Title: Arabidopsis CURLY LEAF functions in leaf immunity against fungal pathogens by concomitantly repressing SEPALLATA3 and activating ORA59.
    4. Plant defensin expression triggered by fungal pathogen invasion depends on EDR1 protein kinase and ORA59 transcription factor in Arabidopsis thaliana.
      Title: Plant defensin expression triggered by fungal pathogen invasion depends on EDR1 protein kinase and ORA59 transcription factor in Arabidopsis thaliana.
    5. enables agmatine coumaryl transferase gene expression and hydroxycinnamic acid amides biosynthesis to respond to simultaneous activation of the JA/ET signaling pathways
      Title: Jasmonic acid/ethylene signaling coordinates hydroxycinnamic acid amides biosynthesis through ORA59 transcription factor.
    6. the opposing function of two transcription factors, ethylene insensitive3 (EIN3) and EIN3-Like1 (EIL1), in salicylic acid-mediated suppression and jasmonic acid-mediated activation of PLANT DEFENSIN1.2 (PDF1.2), through ORA59.
      Title: ORA59 and EIN3 interaction couples jasmonate-ethylene synergistic action to antagonistic salicylic acid regulation of PDF expression.
    7. Salicylic acid exerts a negative effect on the accumulation of the transcription factor ORA59.
      Title: Salicylic acid suppresses jasmonic acid signaling downstream of SCFCOI1-JAZ by targeting GCC promoter motifs via transcription factor ORA59.
    8. ORA59 and two functionally equivalent GCC box binding sites form the module that enables the PDF1.2 gene to respond synergistically to simultaneous activation of the jasmonate and ethylene signaling pathways
      Title: Two GCC boxes and AP2/ERF-domain transcription factor ORA59 in jasmonate/ethylene-mediated activation of the PDF1.2 promoter in Arabidopsis.
    9. ORA59 (AT1g06160) is an essential integrator of the jasmonic acid and ethylene signal transduction pathways.
      Title: The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_100497.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ethylene-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within jasmonic acid and ethylene-dependent systemic resistance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to ethylene IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to jasmonic acid IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular anatomical structure TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    octadecanoid-responsive AP2/ERF 59
    NP_172106.1
    • octadecanoid-responsive Arabidopsis AP2/ERF 59 (ORA59); CONTAINS InterPro DOMAIN/s: DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: ethylene-responsive element binding factor 15 (TAIR:AT2G31230.1); Has 6527 Blast hits to 6261 proteins in 388 species: Archae - 0; Bacteria - 36; Metazoa - 435; Fungi - 42; Plants - 5810; Viruses - 4; Other Eukaryotes - 200 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1882907..1883992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100497.3 → NP_172106.1  octadecanoid-responsive AP2/ERF 59 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172106.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LND1
      UniProtKB/TrEMBL
      A0A178WAR0, A0A5S9SWE7
      Conserved Domains (1) summary
      smart00380
      Location:81 → 145
      AP2; DNA-binding domain in plant proteins such as APETALA2 and EREBPs
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LND1.1

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