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    AHG2 Polynucleotidyl transferase, ribonuclease H-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842037, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AHG2
    Official Full Name
    Polynucleotidyl transferase, ribonuclease H-like superfamily protein
    Primary source
    TAIR:AT1G55870
    Locus tag
    AT1G55870
    See related
    Araport:AT1G55870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ABA-HYPERSENSITIVE GERMINATION 2; ARABIDOPSIS THALIANA POLY(A) RIBONUCLEASE; ATPARN; F14J16.11; F14J16_11
    Summary
    Encodes a poly(A)-specific ribonuclease, AtPARN. Expression of AtPARN is upregulated by ABA or stress treatment. Mutant is hypersensitivity to salicylic acid as well as ABA.
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    Genomic context

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    See AHG2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Sequence:
    Chromosome: 1; NC_003070.9 (20895582..20898868)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene LOW protein: E3 ubiquitin ligase-like protein Neighboring gene ncRNA Neighboring gene ubiquitin-protein ligase Neighboring gene Pyridoxal-5'-phosphate-dependent enzyme family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene Haloacid dehalogenase-like hydrolase (HAD) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A Poly(A) Ribonuclease Controls the Cellotriose-Based Interaction between Piriformospora indica and Its Host Arabidopsis. Johnson JM, et al. Plant Physiol, 2018 Mar. PMID 29371249, Free PMC Article
    2. ABA hypersensitive germination2-1 causes the activation of both abscisic acid and salicylic acid responses in Arabidopsis. Nishimura N, et al. Plant Cell Physiol, 2009 Dec. PMID 19892832
    3. Analysis of ABA hypersensitive germination2 revealed the pivotal functions of PARN in stress response in Arabidopsis. Nishimura N, et al. Plant J, 2005 Dec. PMID 16359390
    4. A poly(A)-specific ribonuclease directly regulates the poly(A) status of mitochondrial mRNA in Arabidopsis. Hirayama T, et al. Nat Commun, 2013. PMID 23912222
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. At1g55870 (Poly(A) Ribonuclease) role in the mutualistic relationship between Piriformospora indica and Arabidopsis.
      Title: A Poly(A) Ribonuclease Controls the Cellotriose-Based Interaction between Piriformospora indica and Its Host Arabidopsis.
    2. AHG2 and AGS1 constitute a regulatory system that controls mitochondrial mRNA poly(A) status in Arabidopsis.
      Title: A poly(A)-specific ribonuclease directly regulates the poly(A) status of mitochondrial mRNA in Arabidopsis.
    3. A partial defect of AHG2/PARN perturbs mitochondrial function independently in addition to the abscisic acid and salicylic acid responses.
      Title: ABA hypersensitive germination2-1 causes the activation of both abscisic acid and salicylic acid responses in Arabidopsis.
    4. AHG2 encodes a poly(A)-specific ribonuclease (AtPARN)that is presumed to function in mRNA degradation. Both upregulation and downregulation of gene expression by AtPARN are crucial for proper ABA, salicylic acid and stress responses. [AHG2]
      Title: Analysis of ABA hypersensitive germination2 revealed the pivotal functions of PARN in stress response in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001333740.1
    NM_001333742.1
    NM_104464.7

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cation binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables poly(A)-specific ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salicylic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Polynucleotidyl transferase, ribonuclease H-like superfamily protein
    NP_001319244.1
    • ABA-HYPERSENSITIVE GERMINATION 2 (AHG2); FUNCTIONS IN: ribonuclease activity, nucleic acid binding; INVOLVED IN: response to abscisic acid stimulus, RNA modification, response to stress, response to salicylic acid stimulus; LOCATED IN: nucleus; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Ribonuclease CAF1 (InterPro:IPR006941), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337); BEST Arabidopsis thaliana protein match is: Polynucleotidyl transferase, ribonuclease H-like superfamily protein (TAIR:AT3G25430.1); Has 352 Blast hits to 351 proteins in 129 species: Archae - 0; Bacteria - 0; Metazoa - 143; Fungi - 63; Plants - 63; Viruses - 0; Other Eukaryotes - 83 (source: NCBI BLink).
    NP_175983.5
    • ABA-HYPERSENSITIVE GERMINATION 2 (AHG2); FUNCTIONS IN: ribonuclease activity, nucleic acid binding; INVOLVED IN: response to abscisic acid stimulus, RNA modification, response to stress, response to salicylic acid stimulus; LOCATED IN: nucleus; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Ribonuclease CAF1 (InterPro:IPR006941), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337); BEST Arabidopsis thaliana protein match is: Polynucleotidyl transferase, ribonuclease H-like superfamily protein (TAIR:AT3G25430.1); Has 452 Blast hits to 437 proteins in 136 species: Archae - 0; Bacteria - 0; Metazoa - 226; Fungi - 62; Plants - 74; Viruses - 0; Other Eukaryotes - 90 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      20895582..20898868
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001333741.1 → NP_001322687.1  Polynucleotidyl transferase, ribonuclease H-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AUW2

    2. NM_104464.7 → NP_175983.5  Polynucleotidyl transferase, ribonuclease H-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175983.5

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q33CQ7, Q33CQ8, Q33CQ9, Q4W7J2, Q9LG26
      UniProtKB/TrEMBL
      A0A178WJN5, A0A5S9WQ37
      Conserved Domains (1) summary
      pfam04857
      Location:41 → 467
      CAF1; CAF1 family ribonuclease

    3. NM_001333742.1 → NP_001322686.1  Polynucleotidyl transferase, ribonuclease H-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LG26

    4. NM_001333740.1 → NP_001319244.1  Polynucleotidyl transferase, ribonuclease H-like superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AUW2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LG26.2

    Gene LinkOut

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