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    Integrin-linked protein kinase family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818989, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Integrin-linked protein kinase family
    Primary source
    TAIR:AT2G43850
    Locus tag
    AT2G43850
    See related
    Araport:AT2G43850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F18O19.4
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    12
    Sequence:
    Chromosome: 2; NC_003071.7 (18159182..18162250, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene UDP-glucosyltransferase 74F2 Neighboring gene miscRNA Neighboring gene UDP-glycosyltransferase 74 F1 Neighboring gene ncRNA Neighboring gene Pectin lyase-like superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Back From the Dead: The Atypical Kinase Activity of a Pseudokinase Regulator of Cation Fluxes During Inducible Immunity. Brauer EK, et al. Front Plant Sci, 2022. PMID 36035673, Free PMC Article
    2. The Raf-like Kinase ILK1 and the High Affinity K+ Transporter HAK5 Are Required for Innate Immunity and Abiotic Stress Response. Brauer EK, et al. Plant Physiol, 2016 Jun. PMID 27208244, Free PMC Article
    3. Genome-wide analysis and experimentation of plant serine/ threonine/tyrosine-specific protein kinases. Rudrabhatla P, et al. Plant Mol Biol, 2006 Jan. PMID 16429265
    4. Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. Nemoto K, et al. Phytochemistry, 2011 Jul. PMID 21477822
    5. Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays. Popescu SC, et al. Proc Natl Acad Sci U S A, 2007 Mar 13. PMID 17360592, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ILK1 interacted with and promoted the accumulation of HAK5, a putative (H(+))/K(+) symporter that mediates a high-affinity uptake during K(+) deficiency.
      Title: The Raf-like Kinase ILK1 and the High Affinity K+ Transporter HAK5 Are Required for Innate Immunity and Abiotic Stress Response.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001337062.1
    NM_129947.4
    NM_201954.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity HDA PubMed 
    enables protein serine/threonine/tyrosine kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within innate immune response IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
    acts_upstream_of_or_within response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic side of plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Integrin-linked protein kinase family
    NP_181913.3
    • Integrin-linked protein kinase family; FUNCTIONS IN: protein serine/threonine/tyrosine kinase activity, kinase activity; INVOLVED IN: regulation of signal transduction, protein amino acid phosphorylation; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Integrin-linked protein kinase (InterPro:IPR016253), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Ankyrin repeat-containing domain (InterPro:IPR020683), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: Integrin-linked protein kinase family (TAIR:AT3G59830.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_973683.1
    • Integrin-linked protein kinase family; FUNCTIONS IN: protein serine/threonine/tyrosine kinase activity, kinase activity; INVOLVED IN: regulation of signal transduction, protein amino acid phosphorylation; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Integrin-linked protein kinase (InterPro:IPR016253), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine-threonine/tyrosine-protein kinase (InterPro:IPR001245), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Ankyrin repeat-containing domain (InterPro:IPR020683), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: Integrin-linked protein kinase family (TAIR:AT3G59830.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      18159182..18162250 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129947.4 → NP_181913.3  Integrin-linked protein kinase family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181913.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4IS56, F4IS57, Q8LL75, Q9SDB3
      UniProtKB/TrEMBL
      A0A178VYB5, A0A5S9X6R7
      Conserved Domains (3) summary
      sd00045
      Location:82 → 108
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:82 → 170
      Ank_2; Ankyrin repeats (3 copies)
      cl21453
      Location:204 → 457
      PKc_like; Protein Kinases, catalytic domain

    2. NM_201954.1 → NP_973683.1  Integrin-linked protein kinase family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973683.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9X6R7
      Conserved Domains (3) summary
      sd00045
      Location:82 → 108
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:82 → 170
      Ank_2; Ankyrin repeats (3 copies)
      cl21453
      Location:212 → 457
      PKc_like; Protein Kinases, catalytic domain

    3. NM_001337062.1 → NP_001324760.1  Integrin-linked protein kinase family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B137, A0A5S9X6R7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4IS56.1

    Gene LinkOut

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