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    Cysteine proteinases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839576, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Cysteine proteinases superfamily protein
    Primary source
    TAIR:AT1G02300
    Locus tag
    AT1G02300
    See related
    Araport:AT1G02300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6A9.28; T7I23.12; T7I23_12
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (453107..455519)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene translocon at the outer envelope membrane of chloroplasts 33 Neighboring gene uncharacterized protein Neighboring gene Cysteine proteinases superfamily protein Neighboring gene ncRNA Neighboring gene Glycosyl hydrolase superfamily protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inhibition of cathepsin B by caspase-3 inhibitors blocks programmed cell death in Arabidopsis. Ge Y, et al. Cell Death Differ, 2016 Sep 1. PMID 27058316, Free PMC Article
    2. Two proteases with caspase-3-like activity, cathepsin B and proteasome, antagonistically control ER-stress-induced programmed cell death in Arabidopsis. Cai YM, et al. New Phytol, 2018 May. PMID 28675441, Free PMC Article
    3. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_100110.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables cysteine-type endopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within proteolysis IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Cysteine proteinases superfamily protein
    NP_563647.1
    • Cysteine proteinases superfamily protein; FUNCTIONS IN: cysteine-type endopeptidase activity, cysteine-type peptidase activity; INVOLVED IN: proteolysis, regulation of catalytic activity; LOCATED IN: endomembrane system; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase C1A, papain (InterPro:IPR013128), Peptidase C1A, cathepsin B (InterPro:IPR015643), Peptidase C1A, papain C-terminal (InterPro:IPR000668), Peptidase, cysteine peptidase active site (InterPro:IPR000169), Peptidase C1A, propeptide (InterPro:IPR012599); BEST Arabidopsis thaliana protein match is: Cysteine proteinases superfamily protein (TAIR:AT1G02305.1); Has 7127 Blast hits to 7085 proteins in 649 species: Archae - 51; Bacteria - 96; Metazoa - 3215; Fungi - 4; Plants - 1554; Viruses - 146; Other Eukaryotes - 2061 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      453107..455519
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100110.3 → NP_563647.1  Cysteine proteinases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563647.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4HVZ1, O23681
      UniProtKB/TrEMBL
      A0A654E623
      Conserved Domains (2) summary
      cd02620
      Location:104 → 357
      Peptidase_C1A_CathepsinB; Cathepsin B group; composed of cathepsin B and similar proteins, including tubulointerstitial nephritis antigen (TIN-Ag). Cathepsin B is a lysosomal papain-like cysteine peptidase which is expressed in all tissues and functions primarily as an ...
      pfam08127
      Location:43 → 85
      Propeptide_C1; Peptidase family C1 propeptide
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4HVZ1.1

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