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    Phosphoglycerate mutase-like family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821297, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Phosphoglycerate mutase-like family protein
    Primary source
    TAIR:AT3G01310
    Locus tag
    AT3G01310
    See related
    Araport:AT3G01310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    Arabidopsis homolog of yeast Vip1 1; AtVIP1; T22N4.6; T22N4_6; T4P13.1; T4P13_1
    Summary
    Encodes a myo-inositol hexakisphosphate kinase.
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    31
    Sequence:
    Chromosome: 3; NC_003074.8 (93995..102010, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene voltage dependent anion channel 1 Neighboring gene SPFH/Band 7/PHB domain-containing membrane-associated protein family Neighboring gene Protein kinase superfamily protein Neighboring gene actin cross-linking protein, putative (DUF569) Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis. Benschop JJ, et al. Mol Cell Proteomics, 2007 Jul. PMID 17317660
    2. VIH2 Regulates the Synthesis of Inositol Pyrophosphate InsP8 and Jasmonate-Dependent Defenses in Arabidopsis. Laha D, et al. Plant Cell, 2015 Apr. PMID 25901085, Free PMC Article
    3. Genetic basis for natural variation in seed vitamin E levels in Arabidopsis thaliana. Gilliland LU, et al. Proc Natl Acad Sci U S A, 2006 Dec 5. PMID 17077148, Free PMC Article
    4. Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis. Zhu J, et al. Elife, 2019 Aug 22. PMID 31436531, Free PMC Article
    5. Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants. Desai M, et al. Plant J, 2014 Nov. PMID 25231822

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001035537.3
    NM_001337329.1
    NM_110997.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 5-diphosphoinositol pentakisphosphate 1-kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables diphosphoinositol pentakisphosphate kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables inositol hexakisphosphate 1-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol hexakisphosphate 3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol hexakisphosphate 5-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol hexakisphosphate kinase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables inositol hexakisphosphate kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables inositol-1,3,4,5,6-pentakisphosphate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in inositol metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within inositol phosphate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in inositol phosphate biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within jasmonic acid and ethylene-dependent systemic resistance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in jasmonic acid and ethylene-dependent systemic resistance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of antifungal innate immune response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of defense response to insect IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of vitamin E biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Phosphoglycerate mutase-like family protein
    NP_001030614.1
    • Phosphoglycerate mutase-like family protein; FUNCTIONS IN: oxidoreductase activity, transition metal ion binding, acid phosphatase activity; INVOLVED IN: oxidation reduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATP-grasp fold, RimK-type (InterPro:IPR013651), Histidine phosphatase superfamily, clade-2 (InterPro:IPR000560), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078); BEST Arabidopsis thaliana protein match is: Phosphoglycerate mutase-like family protein (TAIR:AT5G15070.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_186780.3
    • Phosphoglycerate mutase-like family protein; FUNCTIONS IN: oxidoreductase activity, transition metal ion binding, acid phosphatase activity; INVOLVED IN: oxidation reduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATP-grasp fold, RimK-type (InterPro:IPR013651), Histidine phosphatase superfamily, clade-2 (InterPro:IPR000560), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078); BEST Arabidopsis thaliana protein match is: Phosphoglycerate mutase-like family protein (TAIR:AT5G15070.1); Has 618 Blast hits to 482 proteins in 186 species: Archae - 0; Bacteria - 7; Metazoa - 225; Fungi - 193; Plants - 69; Viruses - 0; Other Eukaryotes - 124 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      93995..102010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001035537.3 → NP_001030614.1  Phosphoglycerate mutase-like family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030614.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4J8C6, Q0WSV1, Q9MAD6, Q9SRH8
      UniProtKB/TrEMBL
      A0A178VBS2, A0A5S9X830
      Conserved Domains (3) summary
      pfam00328
      Location:363 → 953
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:14 → 103
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:103 → 294
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    2. NM_110997.5 → NP_186780.3  Phosphoglycerate mutase-like family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_186780.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VD31, A0A384LD83, A0A5S9X830, F4J8C7
      Conserved Domains (3) summary
      pfam00328
      Location:369 → 959
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:14 → 109
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:109 → 300
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain

    3. NM_001337329.1 → NP_001327831.1  Phosphoglycerate mutase-like family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VEL3, A0A1I9LTI6, A0A384L7F4, A0A5S9X830
      Conserved Domains (3) summary
      pfam00328
      Location:334 → 924
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
      pfam18086
      Location:1 → 74
      PPIP5K2_N; Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain
      cl17255
      Location:74 → 265
      CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    F4J8C6.1

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