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    CRSH Ca2+-activated RelA/spot-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821012, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRSH
    Official Full Name
    Ca2+-activated RelA/spot-like protein
    Primary source
    TAIR:AT3G17470
    Locus tag
    AT3G17470
    See related
    Araport:AT3G17470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCRSH; Ca2+-activated RelA/spot homolog
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    Genomic context

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    See CRSH in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (5979814..5982145)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene hAT dimerization domain-containing protein Neighboring gene PHD finger family protein Neighboring gene ribosomal protein L3 plastid Neighboring gene F-box/associated interaction domain protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The bacterial stringent response, conserved in chloroplasts, controls plant fertilization. Masuda S, et al. Plant Cell Physiol, 2008 Feb. PMID 18178586
    2. Expression profiling of four RelA/SpoT-like proteins, homologues of bacterial stringent factors, in Arabidopsis thaliana. Mizusawa K, et al. Planta, 2008 Sep. PMID 18535838
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis CRSH, localized in chloroplasts, is required for host plant fertilization.[CRSH]
      Title: The bacterial stringent response, conserved in chloroplasts, controls plant fertilization.
    Submit: New GeneRIF Correction

    General gene information

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    NM_112627.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP diphosphokinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTP diphosphokinase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in guanosine tetraphosphate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Ca2+-activated RelA/spot-like protein
    NP_188374.2
    • Ca2+-activated RelA/spot homolog (CRSH); FUNCTIONS IN: GTP diphosphokinase activity, calcium ion binding; INVOLVED IN: guanosine tetraphosphate metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248), RelA/SpoT (InterPro:IPR007685); BEST Arabidopsis thaliana protein match is: RELA/SPOT homolog 3 (TAIR:AT1G54130.1); Has 14021 Blast hits to 13962 proteins in 3173 species: Archae - 6; Bacteria - 8120; Metazoa - 1259; Fungi - 992; Plants - 727; Viruses - 0; Other Eukaryotes - 2917 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5979814..5982145
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001338291.1 → NP_001327079.1  Ca2+-activated RelA/spot-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V9Z0, A0A1I9LR76, A0A5S9XDD3, A0A654F855

    2. NM_001338292.1 → NP_001327078.1  Ca2+-activated RelA/spot-like protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LR75

    3. NM_112627.4 → NP_188374.2  Ca2+-activated RelA/spot-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188374.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q84R11, Q9LUQ0
      UniProtKB/TrEMBL
      A0A178V9Z0, A0A5S9XDD3, A0A654F855
      Conserved Domains (5) summary
      COG0317
      Location:121 → 441
      SpoT; (p)ppGpp synthase/hydrolase, HD superfamily [Signal transduction mechanisms, Transcription]
      pfam04607
      Location:309 → 432
      RelA_SpoT; Region found in RelA / SpoT proteins
      pfam13499
      Location:477 → 529
      EF-hand_7; EF-hand domain pair
      cl08302
      Location:477 → 529
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      cl21469
      Location:108 → 242
      HDc; Metal dependent phosphohydrolases with conserved 'HD' motif
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84R11.1

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