PYD1 pyrimidine 1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: PYD1
Official Full Name: pyrimidine 1
Primary source: TAIR:AT3G17810
Locus tag: AT3G17810
See related: Araport:AT3G17810
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: pyrimidine 1
Summary: Encodes a protein predicted to have dihydropyrimidine dehydrogenase activity. Its activity has not been demonstrated in vivo, but, it is required for efficient uracil catabolism in Arabidopsis. It localizes to the plastid.
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_112662.4

Function	Evidence Code	Pubs
enables dihydropyrimidine dehydrogenase (NADP+) activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables thymine dehydrogenase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in beta-alanine biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cellular response to nitrogen levels	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within uracil catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast stroma	HDA more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info
located_in plastid	IDA Inferred from Direct Assay more info	PubMed

NP_188408.1

pyrimidine 1 (PYD1); FUNCTIONS IN: oxidoreductase activity, acting on the CH-CH group of donors, dihydropyrimidine dehydrogenase (NADP+) activity; INVOLVED IN: 'de novo' pyrimidine base biosynthetic process, uracil catabolic process, cellular response to nitrogen levels; LOCATED IN: chloroplast, plastid; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Dihydroorotate dehydrogenase, class 1/ 2 (InterPro:IPR012135), Dihydroorotate dehydrogenase, class 1, core (InterPro:IPR005720); Has 5953 Blast hits to 5953 proteins in 1914 species: Archae - 176; Bacteria - 4342; Metazoa - 263; Fungi - 99; Plants - 89; Viruses - 0; Other Eukaryotes - 984 (source: NCBI BLink).

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The following sections contain reference sequences that belong to a specific genome build. Explain