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    RNA methyltransferase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821684, updated on 18-Sep-2024

    Summary

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    Official Full Name
    RNA methyltransferase family protein
    Primary source
    TAIR:AT3G21300
    Locus tag
    AT3G21300
    See related
    Araport:AT3G21300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    10
    Sequence:
    Chromosome: 3; NC_003074.8 (7492739..7496371, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene DOF zinc finger protein 2 Neighboring gene ubiquitin carboxyl-terminal hydrolase Neighboring gene dentin sialophosphoprotein-like protein Neighboring gene Tudor/PWWP/MBT superfamily protein Neighboring gene uncharacterized protein Neighboring gene Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein Neighboring gene EARLY FLOWERING protein Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pyrimidine catabolism is required to prevent the accumulation of 5-methyluridine in RNA. Gao S, et al. Nucleic Acids Res, 2023 Aug 11. PMID 37334828, Free PMC Article
    2. Chloroplast RNA-Binding Protein RBD1 Promotes Chilling Tolerance through 23S rRNA Processing in Arabidopsis. Wang S, et al. PLoS Genet, 2016 May. PMID 27138552, Free PMC Article
    3. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    4. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_113025.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to cold IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    RNA methyltransferase family protein
    NP_188767.2
    • RNA methyltransferase family protein; FUNCTIONS IN: RNA binding, RNA methyltransferase activity; INVOLVED IN: RNA processing; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), 23S rRNA methyltransferase/RumA (InterPro:IPR001566), (Uracil-5)-methyltransferase (InterPro:IPR010280), Deoxyribonuclease/rho motif-related TRAM (InterPro:IPR002792); BEST Arabidopsis thaliana protein match is: zinc finger (CCCH-type) family protein (TAIR:AT2G28450.2); Has 10349 Blast hits to 9632 proteins in 2576 species: Archae - 226; Bacteria - 8529; Metazoa - 196; Fungi - 218; Plants - 136; Viruses - 7; Other Eukaryotes - 1037 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      7492739..7496371 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113025.4 → NP_188767.2  RNA methyltransferase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188767.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654F9A3, Q9LU28
      Conserved Domains (3) summary
      COG2265
      Location:71 → 547
      TrmA; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]
      cl01282
      Location:68 → 120
      TRAM; TRAM domain
      cl17173
      Location:272 → 552
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version

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