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    TOM20-3 translocase of outer membrane 20 kDa subunit 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822326, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TOM20-3
    Official Full Name
    translocase of outer membrane 20 kDa subunit 3
    Primary source
    TAIR:AT3G27080
    Locus tag
    AT3G27080
    See related
    Araport:AT3G27080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    translocase of outer membrane 20 kDa subunit 3
    Summary
    Component of the TOM complex involved in transport of nuclear-encoded mitochondrial proteins
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    Genomic context

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    See TOM20-3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (9984947..9986738, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene plant/protein Neighboring gene Ferritin/ribonucleotide reductase-like family protein Neighboring gene translocase outer membrane 20-1 Neighboring gene DCD (Development and Cell Death) domain protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Convergent evolution of receptors for protein import into mitochondria. Perry AJ, et al. Curr Biol, 2006 Feb 7. PMID 16461275
    2. Purification and characterization of the preprotein translocase of the outer mitochondrial membrane from Arabidopsis. Identification of multiple forms of TOM20. Werhahn W, et al. Plant Physiol, 2001 Feb. PMID 11161051, Free PMC Article
    3. Arabidopsis DGD1 SUPPRESSOR1 Is a Subunit of the Mitochondrial Contact Site and Cristae Organizing System and Affects Mitochondrial Biogenesis. Li L, et al. Plant Cell, 2019 Aug. PMID 31118221, Free PMC Article
    4. Functional definition of outer membrane proteins involved in preprotein import into mitochondria. Lister R, et al. Plant Cell, 2007 Nov. PMID 17981999, Free PMC Article
    5. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_113622.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-transporting ATPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein-transporting ATPase activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein insertion into mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein targeting to mitochondrion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to mitochondrion TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of MICOS complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    part_of TIM23 mitochondrial import inner membrane translocase complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrial outer membrane HDA PubMed 
    part_of mitochondrial outer membrane translocase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    translocase of outer membrane 20 kDa subunit 3
    NP_189344.1
    • translocase of outer membrane 20 kDa subunit 3 (TOM20-3); CONTAINS InterPro DOMAIN/s: Plant specific mitochondrial import receptor subunit TOM20 (InterPro:IPR010547); BEST Arabidopsis thaliana protein match is: translocase outer membrane 20-1 (TAIR:AT3G27070.1); Has 97 Blast hits to 97 proteins in 23 species: Archae - 0; Bacteria - 2; Metazoa - 0; Fungi - 0; Plants - 95; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      9984947..9986738 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113622.4 → NP_189344.1  translocase of outer membrane 20 kDa subunit 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189344.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P82874, Q8LBR8, Q9LSC8
      UniProtKB/TrEMBL
      A0A178V7T0, A0A5S9XG15, A0A654FCG4
      Conserved Domains (2) summary
      sd00006
      Location:74 → 115
      TPR; TPR repeat [structural motif]
      pfam06552
      Location:7 → 193
      TOM20_plant; Plant specific mitochondrial import receptor subunit TOM20
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P82874.1

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