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    ELO1 Paxneb protein-like protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820292, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ELO1
    Official Full Name
    Paxneb protein-like protein
    Primary source
    TAIR:AT3G11220
    Locus tag
    AT3G11220
    See related
    Araport:AT3G11220
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ELONGATA 1
    Summary
    A subunit of Elongator, a histone acetyl transferase complex, consisting of six subunits (ELP1#AeiELP6), that copurifies with the elongating RNAPII in yeast and humans. Three Arabidopsis thaliana genes, encoding homologs of the yeast Elongator subunits ELP1, ELP3 (histone acetyl transferase), and ELP4 are responsible for the narrow leaf phenotype in elongata mutants and for reduced root growth that results from a decreased cell division rate.
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    Genomic context

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    See ELO1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (3513350..3516447, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein Neighboring gene alfin-like 2 Neighboring gene SGNH hydrolase-type esterase superfamily protein Neighboring gene Yippee family putative zinc-binding protein Neighboring gene arginine-tRNA protein transferase 2 Neighboring gene Ribosomal protein L10 family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytological investigations of the Arabidopsis thaliana elo1 mutant give new insights into leaf lateral growth and Elongator function. Falcone A, et al. Ann Bot, 2007 Aug. PMID 17565971, Free PMC Article
    2. The elongata mutants identify a functional Elongator complex in plants with a role in cell proliferation during organ growth. Nelissen H, et al. Proc Natl Acad Sci U S A, 2005 May 24. PMID 15894610, Free PMC Article
    3. Evolutionary Conservation in Protein-Protein Interactions and Structures of the Elongator Sub-Complex ELP456 from Arabidopsis and Yeast. Jun SE, et al. Int J Mol Sci, 2024 Apr 15. PMID 38673955, Free PMC Article
    4. Elongator mediates ABA responses, oxidative stress resistance and anthocyanin biosynthesis in Arabidopsis. Zhou X, et al. Plant J, 2009 Oct. PMID 19500300
    5. Plant Elongator regulates auxin-related genes during RNA polymerase II transcription elongation. Nelissen H, et al. Proc Natl Acad Sci U S A, 2010 Jan 26. PMID 20080602, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. show that the Elongator (elo1, elo2, and elo3) complex was purified from plant cell cultures as a six-component complex.
      Title: Plant Elongator regulates auxin-related genes during RNA polymerase II transcription elongation.
    2. Electron microscopy of an elo mutant showed a hypotonic vacuole, alterations in the size of grana and starch grains in the chloroplasts, and the massive presence of Golgi vesicles in the cytoplasm.
      Title: Cytological investigations of the Arabidopsis thaliana elo1 mutant give new insights into leaf lateral growth and Elongator function.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001337916.1
    NM_111957.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to sucrose stimulus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of anthocyanin metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within organ growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of auxin mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of carbon utilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of leaf development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to oxidative stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of elongator holoenzyme complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Paxneb protein-like protein
    NP_001319522.1
    • ELONGATA 1 (ELO1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: cell proliferation, organ growth; LOCATED IN: Elongator holoenzyme complex; CONTAINS InterPro DOMAIN/s: Elongator complex protein 4 (InterPro:IPR008728); Has 305 Blast hits to 280 proteins in 134 species: Archae - 2; Bacteria - 2; Metazoa - 144; Fungi - 81; Plants - 54; Viruses - 0; Other Eukaryotes - 22 (source: NCBI BLink).
    NP_566388.2
    • ELONGATA 1 (ELO1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: cell proliferation, organ growth; LOCATED IN: Elongator holoenzyme complex; CONTAINS InterPro DOMAIN/s: Elongator complex protein 4 (InterPro:IPR008728); Has 319 Blast hits to 294 proteins in 144 species: Archae - 2; Bacteria - 2; Metazoa - 142; Fungi - 99; Plants - 52; Viruses - 0; Other Eukaryotes - 22 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3513350..3516447 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111957.5 → NP_566388.2  Paxneb protein-like protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566388.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4J676, Q4W0V9, Q8W4Q0, Q9C778
      UniProtKB/TrEMBL
      A0A178VAE5, A0A654F762
      Conserved Domains (1) summary
      pfam05625
      Location:20 → 355
      PAXNEB; PAXNEB protein

    2. NM_001337916.1 → NP_001319522.1  Paxneb protein-like protein [Arabidopsis thaliana]

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9C778.1

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