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    CLH1 chlorophyllase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838554, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CLH1
    Official Full Name
    chlorophyllase 1
    Primary source
    TAIR:AT1G19670
    Locus tag
    AT1G19670
    See related
    Araport:AT1G19670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCLH1; ATHCOR1; CHLOROPHYLLASE; chlorophyllase 1; CORI1; CORONATINE-INDUCED PROTEIN 1; F6F9.28; F6F9_28
    Summary
    Chlorophyllase is the first enzyme involved in chlorophyll degradation. It catalyzes the hydrolysis of the ester bond to yield chlorophyllide and phytol. AtCLH1 lacks a typical signal sequence for the chloroplast. Its expression is induced rapidly by methyljasmonate, a known promoter of senescence and chlorophyll degradation.
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    Genomic context

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    See CLH1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (6803486..6805092, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene Wound-responsive family protein Neighboring gene RING/U-box superfamily protein Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene BEL1-like homeodomain 10

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis CHLOROPHYLLASE 1 protects young leaves from long-term photodamage by facilitating FtsH-mediated D1 degradation in photosystem II repair. Tian YN, et al. Mol Plant, 2021 Jul 5. PMID 33857689
    2. Reexamination of chlorophyllase function implies its involvement in defense against chewing herbivores. Hu X, et al. Plant Physiol, 2015 Mar. PMID 25583926, Free PMC Article
    3. Expression of enzymes involved in chlorophyll catabolism in Arabidopsis is light controlled. Banas AK, et al. Plant Physiol, 2011 Nov. PMID 21896889, Free PMC Article
    4. Repression of AtCLH1 expression results in a decrease in the ratio of chlorophyll a/b but doesnot affect the rate of chlorophyll degradation during leaf senescence. Zhou X, et al. Zhi Wu Sheng Li Yu Fen Zi Sheng Wu Xue Xue Bao, 2007 Dec. PMID 18349515
    5. The chlorophyllases AtCLH1 and AtCLH2 are not essential for senescence-related chlorophyll breakdown in Arabidopsis thaliana. Schenk N, et al. FEBS Lett, 2007 Nov 27. PMID 17996203

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis CHLOROPHYLLASE 1 protects young leaves from long-term photodamage by facilitating FtsH-mediated D1 degradation in photosystem II repair.
      Title: Arabidopsis CHLOROPHYLLASE 1 protects young leaves from long-term photodamage by facilitating FtsH-mediated D1 degradation in photosystem II repair.
    2. These results support the presence of a unique binary defense system against insect herbivores involving chlorophyll and CLH.
      Title: Reexamination of chlorophyllase function implies its involvement in defense against chewing herbivores.
    3. The levels of mRNA of two enzymes involved in chlorophyll catabolism in Arabidopsis, products of two chlorophyllase genes, AtCLH1 and AtCLH2, dramatically increase upon illumination with white light.
      Title: Expression of enzymes involved in chlorophyll catabolism in Arabidopsis is light controlled.
    4. Data conclude that AtCLH1 might be required at the initial stage of leaf senescence, quite likely playing a role in converting Chl b to a.
      Title: Repression of AtCLH1 expression results in a decrease in the ratio of chlorophyll a/b but doesnot affect the rate of chlorophyll degradation during leaf senescence.
    5. AtCLHs are not required for senescence-related chlorophyll breakdown in vivo and propose that genuine chlorophyllase has not yet been molecularly identified
      Title: The chlorophyllases AtCLH1 and AtCLH2 are not essential for senescence-related chlorophyll breakdown in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_101823.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables chlorophyllase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chlorophyllase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within chlorophyll catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in chlorophyll catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within defense response to bacterium IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within defense response to fungus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in plant-type vacuole HDA PubMed 

    General protein information

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    Preferred Names
    chlorophyllase 1
    NP_564094.1
    • chlorophyllase 1 (CLH1); FUNCTIONS IN: chlorophyllase activity; INVOLVED IN: response to jasmonic acid stimulus, chlorophyll catabolic process, jasmonic acid mediated signaling pathway, response to stress; LOCATED IN: vacuole; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Chlorophyllase-like (InterPro:IPR010821), Chlorophyllase, chloroplast (InterPro:IPR017395); BEST Arabidopsis thaliana protein match is: chlorophyllase 2 (TAIR:AT5G43860.1); Has 196 Blast hits to 192 proteins in 66 species: Archae - 2; Bacteria - 62; Metazoa - 6; Fungi - 0; Plants - 116; Viruses - 0; Other Eukaryotes - 10 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6803486..6805092 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101823.4 → NP_564094.1  chlorophyllase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564094.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22527
      UniProtKB/TrEMBL
      A0A178W1X2, A0A5S9V8M8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22527.1

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