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    CRF12 AP2 domain-containing transcription factor family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839133, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRF12
    Official Full Name
    AP2 domain-containing transcription factor family protein
    Primary source
    TAIR:AT1G25470
    Locus tag
    AT1G25470
    See related
    Araport:AT1G25470
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cytokinin response factor 12; F2J7.8; F2J7_8
    Summary
    encodes a member of the ERF (ethylene response factor) subfamily B-6 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 12 members in this subfamily including RAP2.11.
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    Genomic context

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    See CRF12 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (8944609..8946628, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene aluminum activated malate transporter family protein Neighboring gene ARM repeat superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Wide-scale screening of T-DNA lines for transcription factor genes affecting male gametophyte development in Arabidopsis. Reňák D, et al. Sex Plant Reprod, 2012 Mar. PMID 22101548
    2. A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis. Smit ME, et al. Plant Cell, 2020 Feb. PMID 31806676, Free PMC Article
    3. Extensive signal integration by the phytohormone protein network. Altmann M, et al. Nature, 2020 Jul. PMID 32612234
    4. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Miscellaneous features

    • Loc: c8945945-8945873 AT1G25470.uORF1-1
    • Loc: c8946243-8946044 AT1G25470.uORF1-2
    NM_102358.4
    NM_202183.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    AP2 domain-containing transcription factor family protein
    NP_173918.2
    • AP2 domain-containing transcription factor family protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Pathogenesis-related genes transcriptional activator PTI6 (InterPro:IPR017392), DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT1G68550.2); Has 2801 Blast hits to 2801 proteins in 148 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 2796; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).
    NP_973912.1
    • AP2 domain-containing transcription factor family protein; FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Pathogenesis-related genes transcriptional activator PTI6 (InterPro:IPR017392), DNA-binding, integrase-type (InterPro:IPR016177), Pathogenesis-related transcriptional factor/ERF, DNA-binding (InterPro:IPR001471); BEST Arabidopsis thaliana protein match is: Integrase-type DNA-binding superfamily protein (TAIR:AT1G68550.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      8944609..8946628 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102358.4 → NP_173918.2  AP2 domain-containing transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173918.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GW17, Q9C6L7
      UniProtKB/TrEMBL
      A0A178WDZ8, A0A7G2DT10
      Conserved Domains (1) summary
      cd00018
      Location:79 → 120
      AP2; DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor ...

    2. NM_202183.2 → NP_973912.1  AP2 domain-containing transcription factor family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973912.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GW17, Q9C6L7
      UniProtKB/TrEMBL
      A0A178WDZ8, A0A7G2DT10
      Conserved Domains (1) summary
      cd00018
      Location:79 → 120
      AP2; DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GW17.1

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