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    ADF8 actin depolymerizing factor 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828037, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ADF8
    Official Full Name
    actin depolymerizing factor 8
    Primary source
    TAIR:AT4G00680
    Locus tag
    AT4G00680
    See related
    Araport:AT4G00680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    actin depolymerizing factor 8; F6N23.12; F6N23_12
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    Genomic context

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    See ADF8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (279596..281072, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RNAhelicase-like 8 Neighboring gene ncRNA Neighboring gene Remorin family protein Neighboring gene UB-like protease 1B Neighboring gene ncRNA Neighboring gene Spc97/Spc98 family of spindle pole body (SBP) component Neighboring gene C2 calcium/lipid-binding plant phosphoribosyltransferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Actin-depolymerizing factor2-mediated actin dynamics are essential for root-knot nematode infection of Arabidopsis. Clément M, et al. Plant Cell, 2009 Sep. PMID 19794115, Free PMC Article
    2. Plant Actin-Depolymerizing Factors Possess Opposing Biochemical Properties Arising from Key Amino Acid Changes throughout Evolution. Nan Q, et al. Plant Cell, 2017 Feb. PMID 28123105, Free PMC Article
    3. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001340260.1
    NM_116293.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within actin filament depolymerization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in actin filament depolymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    actin depolymerizing factor 8
    NP_567182.1
    • actin depolymerizing factor 8 (ADF8); FUNCTIONS IN: actin binding; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; EXPRESSED IN: root, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Actin-binding, cofilin/tropomyosin type (InterPro:IPR002108); BEST Arabidopsis thaliana protein match is: actin depolymerizing factor 11 (TAIR:AT1G01750.1); Has 1612 Blast hits to 1604 proteins in 270 species: Archae - 0; Bacteria - 5; Metazoa - 759; Fungi - 157; Plants - 515; Viruses - 0; Other Eukaryotes - 176 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      279596..281072 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116293.3 → NP_567182.1  actin depolymerizing factor 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567182.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65277, Q570Y6, Q8LCH3
      UniProtKB/TrEMBL
      A0A178V0Z9, A0A5S9XNZ3, A0A654FKQ2
      Conserved Domains (1) summary
      cl15697
      Location:4 → 137
      ADF_gelsolin; Actin depolymerization factor/cofilin- and gelsolin-like domains

    2. NM_001340260.1 → NP_001328554.1  actin depolymerizing factor 8 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B506, A0A654FKQ2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q570Y6.2

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