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    RBP-DR1 RNA-binding protein-defense related 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828090, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RBP-DR1
    Official Full Name
    RNA-binding protein-defense related 1
    Primary source
    TAIR:AT4G03110
    Locus tag
    AT4G03110
    See related
    Araport:AT4G03110
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtBRN1; AtRBP-DR1; BRN1; Bruno-like 1; F4C21.3; RNA-binding protein-defense related 1
    Summary
    Encodes a putative RNA-binding protein that is located in the cytoplasm and is involved in the hypersensitive response and positively regulates salicylic acid-mediated immunity.
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    Genomic context

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    See RBP-DR1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (1376306..1379747, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene sequence-specific DNA binding transcription factor ATNDX Neighboring gene Rho GTPase activating protein with PAK-box/P21-Rho-binding domain-containing protein Neighboring gene Mitochondrial substrate carrier family protein Neighboring gene uncharacterized protein Neighboring gene C2H2 and C2HC zinc fingers superfamily protein Neighboring gene BRCT domain-containing DNA repair protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A putative RNA-binding protein positively regulates salicylic acid-mediated immunity in Arabidopsis. Qi Y, et al. Mol Plant Microbe Interact, 2010 Dec. PMID 20636102
    2. Bruno-like proteins modulate flowering time via 3' UTR-dependent decay of SOC1 mRNA. Kim HS, et al. New Phytol, 2013 May. PMID 23437850
    3. In Planta Determination of the mRNA-Binding Proteome of Arabidopsis Etiolated Seedlings. Reichel M, et al. Plant Cell, 2016 Oct. PMID 27729395, Free PMC Article
    4. Discovering the RNA-Binding Proteome of Plant Leaves with an Improved RNA Interactome Capture Method. Bach-Pages M, et al. Biomolecules, 2020 Apr 24. PMID 32344669, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. At4g03110 and At1g03457 proteins modulate flowering time via 3' UTR-dependent decay of SOC1 mRNA.
      Title: Bruno-like proteins modulate flowering time via 3' UTR-dependent decay of SOC1 mRNA.
    2. AtRBP-DR1 is a positive regulator of salicyclic acid (SA)-mediated immunity, possibly acting on SA signaling-related genes at a post-transcriptional level.
      Title: A putative RNA-binding protein positively regulates salicylic acid-mediated immunity in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_001340422.1
    NM_116545.4
    NM_178963.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables mRNA binding HDA PubMed 
    enables mRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type hypersensitive response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of salicylic acid mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of photoperiodism, flowering IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    RNA-binding protein-defense related 1
    NP_567249.1
    • RNA-binding protein-defense related 1 (RBP-DR1); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: plant-type hypersensitive response, positive regulation of salicylic acid mediated signaling pathway; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Ribonucleoprotein, BRUNO-like (InterPro:IPR015903), Paraneoplastic encephalomyelitis antigen (InterPro:IPR002343), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT1G03457.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_849294.1
    • RNA-binding protein-defense related 1 (RBP-DR1); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; INVOLVED IN: plant-type hypersensitive response, positive regulation of salicylic acid mediated signaling pathway; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), Ribonucleoprotein, BRUNO-like (InterPro:IPR015903), Paraneoplastic encephalomyelitis antigen (InterPro:IPR002343), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: RNA-binding (RRM/RBD/RNP motifs) family protein (TAIR:AT1G03457.1); Has 16162 Blast hits to 12321 proteins in 473 species: Archae - 8; Bacteria - 251; Metazoa - 10325; Fungi - 1647; Plants - 2258; Viruses - 0; Other Eukaryotes - 1673 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1376306..1379747 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_178963.3 → NP_849294.1  RNA-binding protein-defense related 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849294.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V146
      Conserved Domains (2) summary
      cd12361
      Location:19 → 95
      RRM1_2_CELF1-6_like; RNA recognition motif 1 and 2 in CELF/Bruno-like family of RNA binding proteins and plant flowering time control protein FCA
      cl17169
      Location:350 → 397
      RRM_SF; RNA recognition motif (RRM) superfamily

    2. NM_116545.4 → NP_567249.1  RNA-binding protein-defense related 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_567249.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LFS6, Q8VZ45, Q9ZNS7
      UniProtKB/TrEMBL
      A0A178V0R4, A0A5S9XQ98, A0A654FLF9
      Conserved Domains (3) summary
      TIGR01642
      Location:231 → 423
      U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor
      cd12361
      Location:19 → 95
      RRM1_2_CELF1-6_like; RNA recognition motif 1 (RRM1) and 2 (RRM2) found in CELF/Bruno-like family of RNA binding proteins and plant flowering time control protein FCA
      cd12362
      Location:351 → 423
      RRM3_CELF1-6; RNA recognition motif 3 (RRM3) found in CELF/Bruno-like family of RNA binding proteins CELF1, CELF2, CELF3, CELF4, CELF5, CELF6 and similar proteins

    3. NM_001340422.1 → NP_001329301.1  RNA-binding protein-defense related 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178V0R4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LFS6.1

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