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    ORP1C OSBP(oxysterol binding protein)-related protein 1C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 826368, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ORP1C
    Official Full Name
    OSBP(oxysterol binding protein)-related protein 1C
    Primary source
    TAIR:AT4G08180
    Locus tag
    AT4G08180
    See related
    Araport:AT4G08180
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    OSBP(oxysterol binding protein)-related protein 1C; T12G13.20; T12G13_20
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    Genomic context

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    See ORP1C in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Sequence:
    Chromosome: 4; NC_003075.7 (5169459..5174107)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene glycosyl hydrolase family 10 protein / carbohydrate-binding domain-containing protein Neighboring gene Inositol 1,3,4-trisphosphate 5/6-kinase family protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Learning the lipid language of plant signalling. van Leeuwen W, et al. Trends Plant Sci, 2004 Aug. PMID 15358268
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001340578.1
    NM_116887.3
    NM_179012.2
    NM_202789.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidylinositol binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    OSBP(oxysterol binding protein)-related protein 1C
    NP_001319881.1
    • OSBP(oxysterol binding protein)-related protein 1C (ORP1C); FUNCTIONS IN: phosphoinositide binding, oxysterol binding; INVOLVED IN: steroid metabolic process, signal transduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pleckstrin homology-type (InterPro:IPR011993), Oxysterol-binding protein (InterPro:IPR000648), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: OSBP(oxysterol binding protein)-related protein 1A (TAIR:AT2G31020.1); Has 2760 Blast hits to 2567 proteins in 218 species: Archae - 0; Bacteria - 4; Metazoa - 1466; Fungi - 697; Plants - 301; Viruses - 0; Other Eukaryotes - 292 (source: NCBI BLink).
    NP_849343.2
    • OSBP(oxysterol binding protein)-related protein 1C (ORP1C); FUNCTIONS IN: phosphoinositide binding, oxysterol binding; INVOLVED IN: steroid metabolic process, signal transduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pleckstrin homology-type (InterPro:IPR011993), Pleckstrin homology (InterPro:IPR001849), Oxysterol-binding protein (InterPro:IPR000648); BEST Arabidopsis thaliana protein match is: OSBP(oxysterol binding protein)-related protein 1A (TAIR:AT2G31020.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_974518.1
    • OSBP(oxysterol binding protein)-related protein 1C (ORP1C); FUNCTIONS IN: phosphoinositide binding, oxysterol binding; INVOLVED IN: steroid metabolic process, signal transduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pleckstrin homology-type (InterPro:IPR011993), Oxysterol-binding protein (InterPro:IPR000648), Pleckstrin homology (InterPro:IPR001849); BEST Arabidopsis thaliana protein match is: OSBP(oxysterol binding protein)-related protein 1A (TAIR:AT2G31020.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      5169459..5174107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001340578.1 → NP_001319881.1  OSBP(oxysterol binding protein)-related protein 1C [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E6U4, Q56XA3, Q56ZH2, Q8L751, Q9SUG2
      UniProtKB/TrEMBL
      A0A654FM88, A0A7G2F1X7
      Conserved Domains (2) summary
      cd13294
      Location:106 → 242
      PH_ORP_plant; Plant Oxysterol binding protein related protein Pleckstrin homology (PH) domain
      pfam01237
      Location:437 → 789
      Oxysterol_BP; Oxysterol-binding protein

    2. NM_116887.3 → NP_192558.2  OSBP(oxysterol binding protein)-related protein 1C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192558.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3E6U4, Q56XA3, Q56ZH2, Q8L751, Q9SUG2
      UniProtKB/TrEMBL
      A0A654FM88, A0A7G2F1X7
      Conserved Domains (2) summary
      cd13294
      Location:106 → 242
      PH_ORP_plant; Plant Oxysterol binding protein related protein Pleckstrin homology (PH) domain
      pfam01237
      Location:437 → 789
      Oxysterol_BP; Oxysterol-binding protein

    3. NM_202789.1 → NP_974518.1  OSBP(oxysterol binding protein)-related protein 1C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974518.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FM88
      Conserved Domains (3) summary
      cd13294
      Location:106 → 242
      PH_ORP_plant; Plant Oxysterol binding protein related protein Pleckstrin homology (PH) domain
      pfam00169
      Location:108 → 234
      PH; PH domain
      pfam01237
      Location:436 → 788
      Oxysterol_BP; Oxysterol-binding protein

    4. NM_179012.2 → NP_849343.2  OSBP(oxysterol binding protein)-related protein 1C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849343.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654FM88, A0A7G2F1A0, F4JFW6
      Conserved Domains (2) summary
      cd13294
      Location:106 → 242
      PH_ORP_plant; Plant Oxysterol binding protein related protein Pleckstrin homology (PH) domain
      pfam01237
      Location:436 → 788
      Oxysterol_BP; Oxysterol-binding protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L751.1

    Gene LinkOut

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