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    CRK7 cysteine-rich RLK (RECEPTOR-like protein kinase) 7 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828414, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRK7
    Official Full Name
    cysteine-rich RLK (RECEPTOR-like protein kinase) 7
    Primary source
    TAIR:AT4G23150
    Locus tag
    AT4G23150
    See related
    Araport:AT4G23150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cysteine-rich RLK (RECEPTOR-like protein kinase) 7; F21P8.40; F21P8_40
    Summary
    Encodes a cysteine-rich receptor-like protein kinase.
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    Genomic context

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    See CRK7 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    7
    Sequence:
    Chromosome: 4; NC_003075.7 (12125664..12128490)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 5 Neighboring gene cysteine-rich RLK (RECEPTOR-like protein kinase) 6 Neighboring gene cysteine-rich RECEPTOR-like kinase Neighboring gene receptor-like protein kinase-related family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis thaliana cysteine-rich receptor-like kinases CRK6 and CRK7 protect against apoplastic oxidative stress. Idänheimo N, et al. Biochem Biophys Res Commun, 2014 Mar 7. PMID 24530916
    2. MAPK target networks in Arabidopsis thaliana revealed using functional protein microarrays. Popescu SC, et al. Genes Dev, 2009 Jan 1. PMID 19095804, Free PMC Article
    3. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. CRK6 and CRK7 are active protein kinases with differential preference for divalent cations. O3 sensitivity of crk6 and crk7 is disguised by redundancy effect.
      Title: The Arabidopsis thaliana cysteine-rich receptor-like kinases CRK6 and CRK7 protect against apoplastic oxidative stress.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118444.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to reactive oxygen species IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    cysteine-rich RLK (RECEPTOR-like protein kinase) 7
    NP_194046.2
    • cysteine-rich RLK (RECEPTOR-like protein kinase) 7 (CRK7); FUNCTIONS IN: kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: endomembrane system; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Protein of unknown function DUF26 (InterPro:IPR002902), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: cysteine-rich RLK (RECEPTOR-like protein kinase) 8 (TAIR:AT4G23160.1); Has 123287 Blast hits to 121744 proteins in 4655 species: Archae - 106; Bacteria - 14344; Metazoa - 45046; Fungi - 10671; Plants - 34613; Viruses - 423; Other Eukaryotes - 18084 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      12125664..12128490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118444.3 → NP_194046.2  cysteine-rich RLK (RECEPTOR-like protein kinase) 7 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194046.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O65467, Q8L7G3
      UniProtKB/TrEMBL
      A0A5S9XVP6
      Conserved Domains (3) summary
      smart00219
      Location:339 → 603
      TyrKc; Tyrosine kinase, catalytic domain
      cd14066
      Location:342 → 608
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      pfam01657
      Location:32 → 127
      Stress-antifung; Salt stress response/antifungal
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L7G3.1

    Gene LinkOut

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