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    PPX1 protein phosphatase X 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828779, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PPX1
    Official Full Name
    protein phosphatase X 1
    Primary source
    TAIR:AT4G26720
    Locus tag
    AT4G26720
    See related
    Araport:AT4G26720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F10M23.60; F10M23_60; PPX-1; protein phosphatase X 1; PROTEIN PHOSPHATASE X-1
    Summary
    Encodes catalytic subunit of protein phosphatase X. Expressed at very low levels in A. thaliana flowers, leaves, stems and roots.
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    Genomic context

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    See PPX1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (13470030..13472486, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene DNA binding / DNA topoisomerase type I Neighboring gene ATPase, V0 complex, subunit E Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene peroxygenase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis. Nageswaran DC, et al. Nat Plants, 2021 Apr. PMID 33846593, Free PMC Article
    2. Identification and molecular cloning of two homologues of protein phosphatase X from Arabidopsis thaliana. Pérez-Callejón E, et al. Plant Mol Biol, 1993 Dec. PMID 8292782
    3. The Protein Phosphatase 4 and SMEK1 Complex Dephosphorylates HYL1 to Promote miRNA Biogenesis by Antagonizing the MAPK Cascade in Arabidopsis. Su C, et al. Dev Cell, 2017 Jun 5. PMID 28586645
    4. PLATINUM SENSITIVE 2 LIKE impacts growth, root morphology, seed set, and stress responses. Kataya ARA, et al. PLoS One, 2017. PMID 28678890, Free PMC Article
    5. The PP2A regulatory subunit Tap46, a component of the TOR signaling pathway, modulates growth and metabolism in plants. Ahn CS, et al. Plant Cell, 2011 Jan. PMID 21216945, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis.
      Title: HIGH CROSSOVER RATE1 encodes PROTEIN PHOSPHATASE X1 and restricts meiotic crossovers in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_118806.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within reciprocal meiotic recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase X 1
    NP_194402.1
    • protein phosphatase X 1 (PPX1); CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: protein phosphatase X 2 (TAIR:AT5G55260.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13470030..13472486 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118806.6 → NP_194402.1  protein phosphatase X 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194402.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P48529
      UniProtKB/TrEMBL
      A0A178V0Q8, A0A5S9XWI6
      Conserved Domains (1) summary
      cd07415
      Location:3 → 287
      MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P48529.1

    Gene LinkOut

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