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    Protein with RING/U-box and TRAF-like domain [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828901, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Protein with RING/U-box and TRAF-like domain
    Primary source
    TAIR:AT4G27880
    Locus tag
    AT4G27880
    See related
    Araport:AT4G27880
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T27E11.120; T27E11_120
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (13883167..13885063)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Vacuolar iron transporter (VIT) family protein Neighboring gene tRNA-Gln Neighboring gene tRNA-Ala Neighboring gene HSP20-like chaperones superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cysteine protease RD21A regulated by E3 ligase SINAT4 is required for drought-induced resistance to Pseudomonas syringae in Arabidopsis. Liu Y, et al. J Exp Bot, 2020 Sep 19. PMID 32453812
    2. SINAT E3 ligases regulate the stability of the ESCRT component FREE1 in response to iron deficiency in plants. Xiao Z, et al. J Integr Plant Biol, 2020 Sep. PMID 32786047
    3. The tumor necrosis factor receptor-associated factor (TRAF)-like family protein SEVEN IN ABSENTIA 2 (SINA2) promotes drought tolerance in an ABA-dependent manner in Arabidopsis. Bao Y, et al. New Phytol, 2014 Apr. PMID 24350984
    4. The wavy growth 3 E3 ligase family controls the gravitropic response in Arabidopsis roots. Sakai T, et al. Plant J, 2012 Apr. PMID 22122664
    5. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Efroni I, et al. Dev Cell, 2013 Feb 25. PMID 23449474, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_118926.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleus IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Protein with RING/U-box and TRAF-like domain
    NP_194517.1
    • Protein with RING/U-box and TRAF-like domains; FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: multicellular organismal development, protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: mitochondrion, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, SIAH-type (InterPro:IPR013010), Seven In Absentia Homolog-type (InterPro:IPR013323), Seven-in-absentia protein, sina (InterPro:IPR004162), TRAF-type (InterPro:IPR013322); BEST Arabidopsis thaliana protein match is: Protein with RING/U-box and TRAF-like domains (TAIR:AT3G61790.1); Has 1768 Blast hits to 1750 proteins in 698 species: Archae - 0; Bacteria - 0; Metazoa - 1225; Fungi - 9; Plants - 484; Viruses - 0; Other Eukaryotes - 50 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      13883167..13885063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118926.3 → NP_194517.1  Protein with RING/U-box and TRAF-like domain [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194517.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9STN8
      UniProtKB/TrEMBL
      A0A178UWK8, A0A384KY39, A0A7G2F1A6, B3LF90
      Conserved Domains (2) summary
      cd16571
      Location:62 → 100
      RING-HC_SIAHs; RING finger, HC subclass, found in Drosophila melanogaster protein Seven-in-Absentia (sina) and its homologs
      pfam03145
      Location:106 → 305
      Sina; Seven in absentia protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9STN8.1

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