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    RABE1c RAB GTPase homolog 8A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823749, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RABE1c
    Official Full Name
    RAB GTPase homolog 8A
    Primary source
    TAIR:AT3G46060
    Locus tag
    AT3G46060
    See related
    Araport:AT3G46060
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARA-3; ARA3; ATRAB8A; ATRABE1C; RAB GTPase homolog 8A; RAB8A; SMALL GTP-BINDING PROTEIN
    Summary
    small GTP-binding protein (ara-3)
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    Genomic context

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    See RABE1c in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (16917527..16920018)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15A D Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene C2H2-type zinc finger family protein Neighboring gene C2H2-type zinc finger family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A ras-related small GTP-binding protein, RabE1c, regulates stomatal movements and drought stress responses by mediating the interaction with ABA receptors. Chen D, et al. Plant Sci, 2021 May. PMID 33775364
    2. Ethylene regulates monomeric GTP-binding protein gene expression and activity in Arabidopsis. Moshkov IE, et al. Plant Physiol, 2003 Apr. PMID 12692329, Free PMC Article
    3. Arabidopsis RAB8A, RAB8B and RAB8D Proteins Interact with Several RTNLB Proteins and are Involved in the Agrobacterium tumefaciens Infection Process. Huang FC, et al. Plant Cell Physiol, 2021 Dec 3. PMID 34255832
    4. Isolation and analysis of cDNAs encoding small GTP-binding proteins of Arabidopsis thaliana. Anai T, et al. Gene, 1991 Dec 15. PMID 1748311
    5. Arabidopsis Rab-E GTPases exhibit a novel interaction with a plasma-membrane phosphatidylinositol-4-phosphate 5-kinase. Camacho L, et al. J Cell Sci, 2009 Dec 1. PMID 19903693

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis RAB8A, RAB8B and RAB8D Proteins Interact with Several RTNLB Proteins and are Involved in the Agrobacterium tumefaciens Infection Process.
      Title: Arabidopsis RAB8A, RAB8B and RAB8D Proteins Interact with Several RTNLB Proteins and are Involved in the Agrobacterium tumefaciens Infection Process.
    2. RabE1c binds PEX7 and facilitates PEX7 degradation in the presence of immobile GFP-PEX7 accumulated at the membrane [RabE1c]
      Title: Proteomic analysis reveals that the Rab GTPase RabE1c is involved in the degradation of the peroxisomal protein receptor PEX7 (peroxin 7).
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084779.1
    NM_001125308.1
    NM_114475.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within ethylene-activated signaling pathway IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog 8A
    NP_001078248.1
    • ARA3; FUNCTIONS IN: GTP binding; INVOLVED IN: ethylene mediated signaling pathway; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 29695 Blast hits to 29627 proteins in 805 species: Archae - 22; Bacteria - 171; Metazoa - 15449; Fungi - 4249; Plants - 3560; Viruses - 20; Other Eukaryotes - 6224 (source: NCBI BLink).
    NP_001118780.1
    • ARA3; FUNCTIONS IN: GTP binding; INVOLVED IN: ethylene mediated signaling pathway; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_190192.1
    • RAB GTPase homolog 8A (RAB8A); FUNCTIONS IN: GTP binding; INVOLVED IN: ethylene mediated signaling pathway; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G59840.1); Has 29695 Blast hits to 29627 proteins in 805 species: Archae - 22; Bacteria - 171; Metazoa - 15449; Fungi - 4249; Plants - 3560; Viruses - 20; Other Eukaryotes - 6224 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16917527..16920018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114475.4 → NP_190192.1  RAB GTPase homolog 8A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190192.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P28186
      UniProtKB/TrEMBL
      A0A178VAR9, A0A5S9XIR3, A0A7G2FNN0
      Conserved Domains (1) summary
      cd01867
      Location:13 → 180
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

    2. NM_001125308.1 → NP_001118780.1  RAB GTPase homolog 8A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001118780.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P28186
      UniProtKB/TrEMBL
      A0A178VAR9, A0A5S9XIR3, A0A7G2FNN0
      Conserved Domains (1) summary
      cd01867
      Location:13 → 180
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)

    3. NM_001084779.1 → NP_001078248.1  RAB GTPase homolog 8A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078248.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P28186
      UniProtKB/TrEMBL
      A0A178VAR9, A0A5S9XIR3, A0A7G2FNN0
      Conserved Domains (1) summary
      cd01867
      Location:13 → 180
      Rab8_Rab10_Rab13_like; Rab GTPase families 8, 10, 13 (Rab8, Rab10, Rab13)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P28186.1

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