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    Cytidine/deoxycytidylate deaminase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824013, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Cytidine/deoxycytidylate deaminase family protein
    Primary source
    TAIR:AT3G48540
    Locus tag
    AT3G48540
    See related
    Araport:AT3G48540
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (17989798..17992039, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene SNF1-related protein kinase regulatory subunit gamma 1 Neighboring gene SHOOT GRAVITROPISM-like protein Neighboring gene chlorsulfuron/imidazolinone resistant 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The nucleotide metabolome of germinating Arabidopsis thaliana seeds reveals a central role for thymidine phosphorylation in chloroplast development. Niehaus M, et al. Plant Cell, 2022 Sep 27. PMID 35861422, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_114712.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cytidine/deoxycytidylate deaminase family protein
    NP_190423.2
    • Cytidine/deoxycytidylate deaminase family protein; FUNCTIONS IN: hydrolase activity, zinc ion binding, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; CONTAINS InterPro DOMAIN/s: APOBEC/CMP deaminase, zinc-binding (InterPro:IPR016192), CMP/dCMP deaminase, zinc-binding (InterPro:IPR002125), Cytidine deaminase-like (InterPro:IPR016193), Cytidine deaminase (InterPro:IPR015517); Has 3737 Blast hits to 3733 proteins in 1421 species: Archae - 65; Bacteria - 2323; Metazoa - 218; Fungi - 134; Plants - 52; Viruses - 89; Other Eukaryotes - 856 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17989798..17992039 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114712.3 → NP_190423.2  Cytidine/deoxycytidylate deaminase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190423.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VIX5, A0A384KB52, A0MF13, Q1PEH3
      Conserved Domains (1) summary
      cd01286
      Location:69 → 182
      deoxycytidylate_deaminase; Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the ...
    Nucleotide Protein
    Heading Accession and Version

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