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    VPS35C VPS35 homolog C [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824294, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VPS35C
    Official Full Name
    VPS35 homolog C
    Primary source
    TAIR:AT3G51310
    Locus tag
    AT3G51310
    See related
    Araport:AT3G51310
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    VPS35 homolog C
    Summary
    Homolog of yeast retromer subunit VPS35. Part of a retromer-like protein complex involved in endosome to lysosome protein transport.
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    Genomic context

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    See VPS35C in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    21
    Sequence:
    Chromosome: 3; NC_003074.8 (19044331..19049454, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene protein serine/threonine kinase Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene pyridoxal-phosphate-dependent serine hydroxymethyltransferase, putative (DUF632) Neighboring gene RHO-related protein from plants 1 Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis VPS35, a retromer component, is required for vacuolar protein sorting and involved in plant growth and leaf senescence. Yamazaki M, et al. Plant Cell Physiol, 2008 Feb. PMID 18222962
    2. Plant retromer, localized to the prevacuolar compartment and microvesicles in Arabidopsis, may interact with vacuolar sorting receptors. Oliviusson P, et al. Plant Cell, 2006 May. PMID 16582012, Free PMC Article
    3. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_114990.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endosome to lysosome transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in multivesicular body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of retromer complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of retromer complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of retromer, cargo-selective complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    VPS35 homolog C
    NP_190699.3
    • VPS35 homolog C (VPS35C); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: intracellular protein transport, endosome to lysosome transport, retrograde transport, endosome to Golgi; LOCATED IN: microsome, retromer complex, membrane, multivesicular body; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Vacuolar protein sorting-associated protein 35 (InterPro:IPR005378); BEST Arabidopsis thaliana protein match is: VPS35 homolog A (TAIR:AT2G17790.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19044331..19049454 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114990.5 → NP_190699.3  VPS35 homolog C [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190699.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8R7K9, Q9SD18
      UniProtKB/TrEMBL
      A0A178VKA9
      Conserved Domains (1) summary
      pfam03635
      Location:9 → 747
      Vps35; Vacuolar protein sorting-associated protein 35
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8R7K9.1

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