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    EPC1 Nucleotide-diphospho-sugar transferases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824749, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EPC1
    Official Full Name
    Nucleotide-diphospho-sugar transferases superfamily protein
    Primary source
    TAIR:AT3G55830
    Locus tag
    AT3G55830
    See related
    Araport:AT3G55830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ECTOPICALLY PARTING CELLS
    Summary
    A member of the Glycosyltransferase Family 64, homologous to Poplar cambium-expressed GT64 gene. The EPC1 protein plays a critical role during plant development in maintaining the integrity of organs via cell-cell adhesion, thereby providing mechanical strength and facilitating the movement of metabolites throughout the plant.
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    Genomic context

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    See EPC1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (20714946..20717443)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Pyruvate kinase family protein Neighboring gene Fasciclin-like arabinogalactan family protein Neighboring gene Hs1pro-1 protein Neighboring gene Amidohydrolase family Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of Inositol Phosphorylceramide Sphingolipid Mannosylation Induces Plant Immune Responses and Reduces Cellulose Content in Arabidopsis. Fang L, et al. Plant Cell, 2016 Dec. PMID 27895225, Free PMC Article
    2. The ectopically parting cells 1-2 (epc1-2) mutant exhibits an exaggerated response to abscisic acid. Bown L, et al. J Exp Bot, 2007. PMID 17426055
    3. Cell adhesion in Arabidopsis thaliana is mediated by ECTOPICALLY PARTING CELLS 1--a glycosyltransferase (GT64) related to the animal exostosins. Singh SK, et al. Plant J, 2005 Aug. PMID 16045474
    4. Mapping the Arabidopsis organelle proteome. Dunkley TP, et al. Proc Natl Acad Sci U S A, 2006 Apr 25. PMID 16618929, Free PMC Article
    5. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. EPC1 does not affect cell adhesion but has a role in processes affecting plant growth and development.
      Title: The ectopically parting cells 1-2 (epc1-2) mutant exhibits an exaggerated response to abscisic acid.
    Submit: New GeneRIF Correction

    General gene information

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    NM_115441.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables UDP-glucosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables glycosyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables glycosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mannosylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pectic galactan metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phloem or xylem histogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type cell wall cellulose metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plant-type hypersensitive response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sphingolipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endosome HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in trans-Golgi network HDA PubMed 

    General protein information

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    Preferred Names
    Nucleotide-diphospho-sugar transferases superfamily protein
    NP_191142.1
    • ECTOPICALLY PARTING CELLS (EPC1); CONTAINS InterPro DOMAIN/s: EXTL2, alpha-1,4-N-acetylhexosaminyltransferase (InterPro:IPR015338); BEST Arabidopsis thaliana protein match is: glycosyltransferase family protein 47 (TAIR:AT5G04500.1); Has 655 Blast hits to 655 proteins in 91 species: Archae - 0; Bacteria - 0; Metazoa - 500; Fungi - 8; Plants - 105; Viruses - 0; Other Eukaryotes - 42 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      20714946..20717443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_115441.3 → NP_191142.1  Nucleotide-diphospho-sugar transferases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191142.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LY62
      UniProtKB/TrEMBL
      A0A178VJT0, A0A5S9XMW2, A0A654FH86
      Conserved Domains (1) summary
      pfam09258
      Location:74 → 325
      Glyco_transf_64; Glycosyl transferase family 64 domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LY62.1

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