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    CYSC1 cysteine synthase C1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825317, updated on 18-Sep-2024

    Summary

    Official Symbol
    CYSC1
    Official Full Name
    cysteine synthase C1
    Primary source
    TAIR:AT3G61440
    Locus tag
    AT3G61440
    See related
    Araport:AT3G61440
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARATH;BSAS3;1; ATCYSC1; BETA-SUBSTITUTED ALA SYNTHASE 3;1; CYSTEINE SYNTHASE; cysteine synthase C1; CYSTEINE SYNTHASE C1
    Summary
    Encodes a cysteine synthase isomer CysC1. The isomer is however less effective in cysteine biosynthesis. It is involved in beta-cyanoalanine biosynthesis, an intermediate of cyanide detoxification pathway.
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    Genomic context

    See CYSC1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    10
    Sequence:
    Chromosome: 3; NC_003074.8 (22735663..22738131)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene BSD domain (BTF2-like transcription factors, Synapse-associated proteins and DOS2-like proteins) Neighboring gene plasma membrane intrinsic protein 1A Neighboring gene syntaxin of plants 73 Neighboring gene brassinosteroid-responsive RING-H2

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    General gene information

    NM_001084855.2
    NM_001203223.1
    NM_001340099.1
    NM_116009.4

    Gene Ontology Provided by TAIR

    General protein information

    Preferred Names
    cysteine synthase C1
    NP_001078324.1
    • CYSTEINE SYNTHASE C1 (ATCYSC1); FUNCTIONS IN: cysteine synthase activity, copper ion binding, L-3-cyanoalanine synthase activity; INVOLVED IN: cysteine biosynthetic process, detoxification of nitrogen compound, cyanide metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Cysteine synthase A (InterPro:IPR005859); BEST Arabidopsis thaliana protein match is: O-acetylserine (thiol) lyase isoform C (TAIR:AT3G59760.1); Has 18552 Blast hits to 18542 proteins in 2624 species: Archae - 313; Bacteria - 12869; Metazoa - 388; Fungi - 549; Plants - 552; Viruses - 2; Other Eukaryotes - 3879 (source: NCBI BLink).
    NP_001190152.1
    • cysteine synthase C1 (CYSC1); CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926); BEST Arabidopsis thaliana protein match is: O-acetylserine (thiol) lyase isoform C (TAIR:AT3G59760.3).
    NP_191703.1
    • cysteine synthase C1 (CYSC1); FUNCTIONS IN: cysteine synthase activity, copper ion binding, L-3-cyanoalanine synthase activity; INVOLVED IN: cysteine biosynthetic process, detoxification of nitrogen compound, cyanide metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site (InterPro:IPR001216), Cysteine synthase A (InterPro:IPR005859), Pyridoxal phosphate-dependent enzyme, beta subunit (InterPro:IPR001926), Cysteine synthase K/M (InterPro:IPR005856); BEST Arabidopsis thaliana protein match is: O-acetylserine (thiol) lyase isoform C (TAIR:AT3G59760.3); Has 22016 Blast hits to 21996 proteins in 2681 species: Archae - 390; Bacteria - 15417; Metazoa - 417; Fungi - 652; Plants - 575; Viruses - 2; Other Eukaryotes - 4563 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22735663..22738131
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001203223.1 → NP_001190152.1  cysteine synthase C1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190152.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S757
      Conserved Domains (1) summary
      cl00342
      Location:1 → 247
      Trp-synth-beta_II; Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan ...
    2. NM_116009.4 → NP_191703.1  cysteine synthase C1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191703.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4JEA0, F4JEA1, Q9S757
      UniProtKB/TrEMBL
      A0A178VGN1, A0A5S9XPI6
      Conserved Domains (1) summary
      PLN02556
      Location:1 → 368
      PLN02556; cysteine synthase/L-3-cyanoalanine synthase
    3. NM_001340099.1 → NP_001327883.1  cysteine synthase C1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LTP2, A0A5S9XPI6
    4. NM_001084855.2 → NP_001078324.1  cysteine synthase C1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078324.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9S757
      Conserved Domains (1) summary
      cl00342
      Location:1 → 272
      Trp-synth-beta_II; Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan ...
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