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    PANB2 Phosphoenolpyruvate carboxylase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 825326, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PANB2
    Official Full Name
    Phosphoenolpyruvate carboxylase family protein
    Primary source
    TAIR:AT3G61530
    Locus tag
    AT3G61530
    See related
    Araport:AT3G61530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    KETOPANTOATE HYDROXYMETHYLTRANSFERASE; KPHMT2
    Summary
    Encodes a ketopentoate hydroxymethyltransferase that appears to localize to the mitochondria. This protein is expected to play a role in pantothenate (vitamin B5) biosynthesis.
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    Genomic context

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    See PANB2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (22771405..22773790, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ACC synthase 1 Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene tRNA-Glu Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Organisation of the pantothenate (vitamin B5) biosynthesis pathway in higher plants. Ottenhof HH, et al. Plant J, 2004 Jan. PMID 14675432
    2. Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function. Tan YF, et al. Plant Physiol, 2010 Feb. PMID 20018591, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_116018.4
    NM_202745.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 3-methyl-2-oxobutanoate hydroxymethyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 3-methyl-2-oxobutanoate hydroxymethyltransferase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables cobalt ion binding HDA PubMed 
    enables zinc ion binding HDA PubMed 
    Process Evidence Code Pubs
    involved_in pantothenate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pantothenate biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Phosphoenolpyruvate carboxylase family protein
    NP_191712.1
    • PANB2; CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Ketopantoate hydroxymethyltransferase (InterPro:IPR003700); BEST Arabidopsis thaliana protein match is: ketopantoate hydroxymethyltransferase 1 (TAIR:AT2G46110.1); Has 7570 Blast hits to 7570 proteins in 2036 species: Archae - 128; Bacteria - 4151; Metazoa - 4; Fungi - 140; Plants - 59; Viruses - 0; Other Eukaryotes - 3088 (source: NCBI BLink).
    NP_974474.1
    • PANB2; CONTAINS InterPro DOMAIN/s: Pyruvate/Phosphoenolpyruvate kinase, catalytic core (InterPro:IPR015813), Ketopantoate hydroxymethyltransferase (InterPro:IPR003700); BEST Arabidopsis thaliana protein match is: ketopantoate hydroxymethyltransferase 1 (TAIR:AT2G46110.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      22771405..22773790 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202745.4 → NP_974474.1  Phosphoenolpyruvate carboxylase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974474.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M315
      UniProtKB/TrEMBL
      A0A5S9XMS8, A0A654FJS9
      Conserved Domains (1) summary
      PLN02424
      Location:23 → 354
      PLN02424; ketopantoate hydroxymethyltransferase

    2. NM_116018.4 → NP_191712.1  Phosphoenolpyruvate carboxylase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_191712.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9M315
      UniProtKB/TrEMBL
      A0A5S9XMS8, A0A654FJS9
      Conserved Domains (1) summary
      PLN02424
      Location:23 → 354
      PLN02424; ketopantoate hydroxymethyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M315.1

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