DFB DHFS-FPGS homolog B [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: DFB
Official Full Name: DHFS-FPGS homolog B
Primary source: TAIR:AT5G05980
Locus tag: AT5G05980
See related: Araport:AT5G05980
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATDFB; DHFS-FPGS homolog B; folylpolyglutamate synthetase 1; FPGS1; K18J17.17; K18J17_17
Summary: Encodes one of the three folylpolyglutamate synthetase isoforms (FPGSs): FPGS1 (At5g05980, plastidic), FPGS2 (At3g10160, mitochondrial) and FPGS3 (At3g55630, cytosolic).
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Chromosome 5 - NC_003076.8 Genomic Context describing neighboring genes

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NM_001036763.2

NM_120680.3

Function	Evidence Code	Pubs
enables tetrahydrofolylpolyglutamate synthase activity	IGI Inferred from Genetic Interaction more info	PubMed
enables tetrahydrofolylpolyglutamate synthase activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within lignin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within one-carbon metabolic process	TAS Traceable Author Statement more info	PubMed
acts_upstream_of_or_within quiescent center organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within root development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within root hair elongation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within root meristem growth	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in tetrahydrofolylpolyglutamate biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tetrahydrofolylpolyglutamate biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast stroma	IDA Inferred from Direct Assay more info	PubMed

NP_001031840.1

DHFS-FPGS homolog B (DFB); CONTAINS InterPro DOMAIN/s: Folylpolyglutamate synthetase, conserved site (InterPro:IPR018109), Mur ligase, central (InterPro:IPR013221), Mur ligase, C-terminal (InterPro:IPR004101), Folylpolyglutamate synthetase (InterPro:IPR001645); BEST Arabidopsis thaliana protein match is: DHFS-FPGS homolog D (TAIR:AT3G55630.3); Has 7710 Blast hits to 7708 proteins in 2543 species: Archae - 43; Bacteria - 4850; Metazoa - 165; Fungi - 360; Plants - 132; Viruses - 0; Other Eukaryotes - 2160 (source: NCBI BLink).

NP_196217.2

DHFS-FPGS homolog B (DFB); CONTAINS InterPro DOMAIN/s: Folylpolyglutamate synthetase, conserved site (InterPro:IPR018109), Mur ligase, central (InterPro:IPR013221), Mur ligase, C-terminal (InterPro:IPR004101), Folylpolyglutamate synthetase (InterPro:IPR001645); BEST Arabidopsis thaliana protein match is: DHFS-FPGS homolog D (TAIR:AT3G55630.3); Has 7626 Blast hits to 7624 proteins in 2505 species: Archae - 43; Bacteria - 4775; Metazoa - 165; Fungi - 350; Plants - 132; Viruses - 0; Other Eukaryotes - 2161 (source: NCBI BLink).