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    STRS2 DEA(D/H)-box RNA helicase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 830763, updated on 18-Sep-2024

    Summary

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    Official Symbol
    STRS2
    Official Full Name
    DEA(D/H)-box RNA helicase family protein
    Primary source
    TAIR:AT5G08620
    Locus tag
    AT5G08620
    See related
    Araport:AT5G08620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRH25; MAH20.18; MAH20_18; RNA HELICASE 25; STRESS RESPONSE SUPPRESSOR 2
    Summary
    Similar in sequence to DEAD-box RNA helicases. Binds RNA. Involved in drought, salt and cold stress responses.
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    Genomic context

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    See STRS2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (2794388..2797760)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene U3 ribonucleoprotein (Utp) family protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene DDT domain-containing protein Neighboring gene flavonol synthase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DEAD-box RNA helicases and epigenetic control of abiotic stress-responsive gene expression. Barak S, et al. Plant Signal Behav, 2014. PMID 25517295, Free PMC Article
    2. The Arabidopsis STRESS RESPONSE SUPPRESSOR DEAD-box RNA helicases are nucleolar- and chromocenter-localized proteins that undergo stress-mediated relocalization and are involved in epigenetic gene silencing. Khan A, et al. Plant J, 2014 Jul. PMID 24724701
    3. Functional characterization of DEAD-box RNA helicases in Arabidopsis thaliana under abiotic stress conditions. Kim JS, et al. Plant Cell Physiol, 2008 Oct. PMID 18725370
    4. STRESS RESPONSE SUPPRESSOR1 and STRESS RESPONSE SUPPRESSOR2, two DEAD-box RNA helicases that attenuate Arabidopsis responses to multiple abiotic stresses. Kant P, et al. Plant Physiol, 2007 Nov. PMID 17556511, Free PMC Article
    5. 14-3-3 proteins fine-tune plant nutrient metabolism. Shin R, et al. FEBS Lett, 2011 Jan 3. PMID 21094157

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. the STRSs are localized to the nucleolus and chromocenters, and are rapidly removed to the nucleoplasm upon application of various abiotic stresses.
      Title: DEAD-box RNA helicases and epigenetic control of abiotic stress-responsive gene expression.
    2. The STRS proteins are involved in epigenetic silencing of gene expression to bring about suppression of the Arabidopsis stress response.
      Title: The Arabidopsis STRESS RESPONSE SUPPRESSOR DEAD-box RNA helicases are nucleolar- and chromocenter-localized proteins that undergo stress-mediated relocalization and are involved in epigenetic gene silencing.
    3. RH25 enhances freezing tolerance in Arabidopsis and functions as an RNA chaperone during the cold adaptation process. AtRH9 and AtRH25 affect seed germination under salt stress conditions.
      Title: Functional characterization of DEAD-box RNA helicases in Arabidopsis thaliana under abiotic stress conditions.
    4. suggest that STRS1 and STRS2 attenuate the expression of stress-responsive transcriptional activators and function in abiotic stress signaling networks
      Title: STRESS RESPONSE SUPPRESSOR1 and STRESS RESPONSE SUPPRESSOR2, two DEAD-box RNA helicases that attenuate Arabidopsis responses to multiple abiotic stresses.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_120949.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to cold IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water deprivation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DEA(D/H)-box RNA helicase family protein
    NP_196479.1
    • STRESS RESPONSE SUPPRESSOR 2 (STRS2); CONTAINS InterPro DOMAIN/s: RNA helicase, DEAD-box type, Q motif (InterPro:IPR014014), DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT5G08610.1); Has 41509 Blast hits to 40723 proteins in 3007 species: Archae - 766; Bacteria - 20755; Metazoa - 6012; Fungi - 4615; Plants - 2552; Viruses - 14; Other Eukaryotes - 6795 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      2794388..2797760
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_120949.4 → NP_196479.1  DEA(D/H)-box RNA helicase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_196479.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94C75, Q9ZS00
      UniProtKB/TrEMBL
      A0A178U7J5, A0A5S9Y2K8, A0A654FZI1
      Conserved Domains (1) summary
      COG0513
      Location:69 → 488
      SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q94C75.2

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