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    GSO2 Leucine-rich repeat transmembrane protein kinase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834499, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GSO2
    Official Full Name
    Leucine-rich repeat transmembrane protein kinase
    Primary source
    TAIR:AT5G44700
    Locus tag
    AT5G44700
    See related
    Araport:AT5G44700
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    EDA23; EMBRYO SAC DEVELOPMENT ARREST 23; GASSHO 2; K23L20.3; K23L20_3
    Summary
    Encodes GASSHO2 (GSO2), a putative leucine-rich repeat transmembrane-type receptor kinase. GSO2 and a homolog GSO1 (At4g20140) are required for the formation of a normal epidermal surface during embryogenesis.
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    Genomic context

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    See GSO2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    2
    Sequence:
    Chromosome: 5; NC_003076.8 (18032864..18037323, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene DNA glycosylase superfamily protein Neighboring gene RING finger PFF0165c-like protein Neighboring gene tRNA-Thr Neighboring gene 37S ribosomal protein S27

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2. Okuda S, et al. Proc Natl Acad Sci U S A, 2020 Feb 4. PMID 31964818, Free PMC Article
    2. The receptor-like kinases GSO1 and GSO2 together regulate root growth in Arabidopsis through control of cell division and cell fate specification. Racolta A, et al. Dev Dyn, 2014 Feb. PMID 24123341
    3. GASSHO1 and GASSHO2 encoding a putative leucine-rich repeat transmembrane-type receptor kinase are essential for the normal development of the epidermal surface in Arabidopsis embryos. Tsuwamoto R, et al. Plant J, 2008 Apr. PMID 18088309
    4. SERKs regulate embryonic cuticle integrity through the TWS1-GSO1/2 signaling pathway in Arabidopsis. Zhang H, et al. New Phytol, 2022 Jan. PMID 34614228
    5. A peptide hormone required for Casparian strip diffusion barrier formation in Arabidopsis roots. Nakayama T, et al. Science, 2017 Jan 20. PMID 28104889

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SERKs regulate embryonic cuticle integrity through the TWS1-GSO1/2 signaling pathway in Arabidopsis.
      Title: SERKs regulate embryonic cuticle integrity through the TWS1-GSO1/2 signaling pathway in Arabidopsis.
    2. GSO1/SGN3 and GSO2 have evolved unique peptide binding properties to control different developmental processes.
      Title: Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2.
    3. The receptor-like kinases GSO1 and GSO2 together regulate root growth in Arabidopsis through control of cell division and cell fate specification.
      Title: The receptor-like kinases GSO1 and GSO2 together regulate root growth in Arabidopsis through control of cell division and cell fate specification.
    4. The results of this study suggest that GASSHO1 and GASSHO2 genes are essential for the formation of a normal epidermal surface during embryogenesis.[GASSHO2] [GSO2]
      Title: GASSHO1 and GASSHO2 encoding a putative leucine-rich repeat transmembrane-type receptor kinase are essential for the normal development of the epidermal surface in Arabidopsis embryos.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123837.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in Casparian strip assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo development ending in seed dormancy IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within embryo sac development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within plant epidermis development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell fate specification IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of root morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in specification of plant organ axis polarity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Casparian strip IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Leucine-rich repeat transmembrane protein kinase
    NP_199283.1
    • GASSHO 2 (GSO2); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, ATP binding; INVOLVED IN: protein amino acid phosphorylation, transmembrane receptor protein tyrosine kinase signaling pathway, embryo sac development, embryo development, epidermis development; LOCATED IN: endomembrane system; EXPRESSED IN: 13 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase (TAIR:AT4G20140.1); Has 300710 Blast hits to 146614 proteins in 5000 species: Archae - 184; Bacteria - 28098; Metazoa - 99114; Fungi - 12121; Plants - 127107; Viruses - 448; Other Eukaryotes - 33638 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      18032864..18037323 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123837.3 → NP_199283.1  Leucine-rich repeat transmembrane protein kinase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199283.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FIZ3
      UniProtKB/TrEMBL
      A0A5S9YB09
      Conserved Domains (6) summary
      PLN00113
      Location:285 → 1232
      PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
      cd00116
      Location:603 → 843
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd14066
      Location:954 → 1232
      STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
      sd00033
      Location:290 → 313
      LRR_RI; leucine-rich repeat [structural motif]
      pfam08263
      Location:28 → 68
      LRRNT_2; Leucine rich repeat N-terminal domain
      pfam13855
      Location:240 → 300
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FIZ3.2

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