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    CRR1 Dihydrodipicolinate reductase, bacterial/plant [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835286, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CRR1
    Official Full Name
    Dihydrodipicolinate reductase, bacterial/plant
    Primary source
    TAIR:AT5G52100
    Locus tag
    AT5G52100
    See related
    Araport:AT5G52100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    chlororespiration reduction 1; MSG15.20; MSG15_20
    Summary
    Is essential for chloroplast NAD(P)H dehydrogenase activity, which is involved in electron transfer between PSII and PSI. Likely functions in biogenesis or stabilization of the NAD(P)H dehydrogenase complex.
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    Genomic context

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    See CRR1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    10
    Sequence:
    Chromosome: 5; NC_003076.8 (21170048..21172346)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene chaperone (DUF2930) Neighboring gene ribonuclease H superfamily polynucleotidyl transferase Neighboring gene phloem protein 2-A14

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dihydrodipicolinate reductase-like protein, CRR1, is essential for chloroplast NAD(P)H dehydrogenase in Arabidopsis. Shimizu H, et al. Plant J, 2007 Nov. PMID 17727612
    2. Biosynthesis of lysine in plants: evidence for a variant of the known bacterial pathways. Hudson AO, et al. Biochim Biophys Acta, 2005 Jan 18. PMID 15652176
    3. Multistep assembly of chloroplast NADH dehydrogenase-like subcomplex A requires several nucleus-encoded proteins, including CRR41 and CRR42, in Arabidopsis. Peng L, et al. Plant Cell, 2012 Jan. PMID 22274627, Free PMC Article
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. results suggest that CRR1 is involved in biogenesis or stabilization of the NDH complex, possibly via the reduction of an unknown substrate
      Title: Dihydrodipicolinate reductase-like protein, CRR1, is essential for chloroplast NAD(P)H dehydrogenase in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    NM_124589.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4-hydroxy-tetrahydrodipicolinate reductase IEA
    Inferred from Electronic Annotation
    more info
    		  
    NOT enables 4-hydroxy-tetrahydrodipicolinate reductase IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in lysine biosynthetic process via diaminopimelate IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within photosynthesis, light reaction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Dihydrodipicolinate reductase, bacterial/plant
    NP_200023.1
    • chlororespiration reduction 1 (crr1); FUNCTIONS IN: dihydrodipicolinate reductase activity; INVOLVED IN: photosynthesis, light reaction, lysine biosynthetic process via diaminopimelate; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dihydrodipicolinate reductase, C-terminal (InterPro:IPR022663), NAD(P)-binding domain (InterPro:IPR016040), Dihydrodipicolinate reductase, bacterial/plant (InterPro:IPR011770), Dihydrodipicolinate reductase, N-terminal (InterPro:IPR000846); Has 2708 Blast hits to 2708 proteins in 1059 species: Archae - 78; Bacteria - 2168; Metazoa - 0; Fungi - 0; Plants - 45; Viruses - 0; Other Eukaryotes - 417 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21170048..21172346
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124589.3 → NP_200023.1  Dihydrodipicolinate reductase, bacterial/plant [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200023.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LG90, Q9FJ82
      UniProtKB/TrEMBL
      A0A178UH15, A0A5S9YDH6
      Conserved Domains (1) summary
      cl29298
      Location:34 → 298
      DapB_C; Dihydrodipicolinate reductase, C-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FJ82.1

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