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    SHA1 RING/FYVE/PHD zinc finger superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 836498, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SHA1
    Official Full Name
    RING/FYVE/PHD zinc finger superfamily protein
    Primary source
    TAIR:AT5G63780
    Locus tag
    AT5G63780
    See related
    Araport:AT5G63780
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MBK5.26; MBK5_26; shoot apical meristem arrest 1
    Summary
    Encodes SHA1 (shoot apical meristem arrest), a putative E3 ligase (a RING finger protein) required for post-embryonic SAM maintenance. The mutant sha1-1 shows a primary SAM-deficient phenotype at the adult stage.
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    Genomic context

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    See SHA1 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (25523827..25526593)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene diacylglycerol kinase 2 Neighboring gene NAC domain containing protein 102 Neighboring gene Glycosyl hydrolase family 35 protein Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SHA1, a novel RING finger protein, functions in shoot apical meristem maintenance in Arabidopsis. Sonoda Y, et al. Plant J, 2007 May. PMID 17461786
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001345611.1
    NM_125773.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within maintenance of shoot apical meristem identity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within meristem development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RING/FYVE/PHD zinc finger superfamily protein
    NP_201183.2
    • shoot apical meristem arrest 1 (SHA1); FUNCTIONS IN: zinc ion binding; INVOLVED IN: maintenance of shoot apical meristem identity, meristem development; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-CH-type (InterPro:IPR011016); BEST Arabidopsis thaliana protein match is: RING/FYVE/PHD zinc finger superfamily protein (TAIR:AT5G08750.2); Has 328 Blast hits to 324 proteins in 18 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 327; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      25523827..25526593
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125773.4 → NP_201183.2  RING/FYVE/PHD zinc finger superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_201183.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654GEU5, A0A7G2FLI2, Q8GUG6
      Conserved Domains (1) summary
      cl17238
      Location:135 → 169
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. NM_001345611.1 → NP_001331890.1  RING/FYVE/PHD zinc finger superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654GEU5, A0A7G2FLI2, Q8GUG6
      Conserved Domains (1) summary
      cl17238
      Location:135 → 169
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein
    Heading Accession and Version

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