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    NS1 Class II aminoacyl-tRNA and biotin synthetases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827443, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NS1
    Official Full Name
    Class II aminoacyl-tRNA and biotin synthetases superfamily protein
    Primary source
    TAIR:AT4G17300
    Locus tag
    AT4G17300
    See related
    Araport:AT4G17300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATNS1; DL4685W; FCAALL.396; OVA8; ovule abortion 8
    Summary
    Asparaginyl-tRNA synthetase protein involved in amino acid activation/protein synthesis.
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    Genomic context

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    See NS1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    14
    Sequence:
    Chromosome: 4; NC_003075.7 (9681348..9684984)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Mo25 family protein Neighboring gene Auxin-responsive family protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene G2484-1 protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and expression of an asparaginyl-tRNA synthetase gene located on chromosome IV of Arabidopsis thaliana and adjacent to a novel gene of 15 exons. Aubourg S, et al. Biochim Biophys Acta, 1998 Jul 9. PMID 9655910
    2. Duplication and quadruplication of Arabidopsis thaliana cysteinyl- and asparaginyl-tRNA synthetase genes of organellar origin. Peeters NM, et al. J Mol Evol, 2000 May. PMID 10824085
    3. Dual targeting is the rule for organellar aminoacyl-tRNA synthetases in Arabidopsis thaliana. Duchêne AM, et al. Proc Natl Acad Sci U S A, 2005 Nov 8. PMID 16251277, Free PMC Article
    4. Requirement of aminoacyl-tRNA synthetases for gametogenesis and embryo development in Arabidopsis. Berg M, et al. Plant J, 2005 Dec. PMID 16297076
    5. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_117835.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables asparagine-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables asparagine-tRNA ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in asparaginyl-tRNA aminoacylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within asparaginyl-tRNA aminoacylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within plant ovule development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Class II aminoacyl-tRNA and biotin synthetases superfamily protein
    NP_193462.1
    • NS1; FUNCTIONS IN: asparagine-tRNA ligase activity; INVOLVED IN: asparaginyl-tRNA aminoacylation, ovule development; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Asparaginyl-tRNA synthetase, class IIb (InterPro:IPR004522), Aminoacyl-tRNA synthetase, class II, conserved domain (InterPro:IPR006195), Aspartyl/Asparaginyl-tRNA synthetase, class IIb (InterPro:IPR002312), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Aminoacyl-tRNA synthetase, class II (D/K/N) (InterPro:IPR004364), Aminoacyl-tRNA synthetase, class II (D/K/N)-like (InterPro:IPR018150); BEST Arabidopsis thaliana protein match is: Class II aminoacyl-tRNA and biotin synthetases superfamily protein (TAIR:AT1G70980.1); Has 19374 Blast hits to 17086 proteins in 2835 species: Archae - 447; Bacteria - 14373; Metazoa - 505; Fungi - 670; Plants - 294; Viruses - 0; Other Eukaryotes - 3085 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      9681348..9684984
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341198.1 → NP_001328216.1  Class II aminoacyl-tRNA and biotin synthetases superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UXJ8, A0A1P8B3X2
      Conserved Domains (1) summary
      PLN02603
      Location:21 → 587
      PLN02603; asparaginyl-tRNA synthetase

    2. NM_117835.5 → NP_193462.1  Class II aminoacyl-tRNA and biotin synthetases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193462.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23573, O48593, Q564D6
      UniProtKB/TrEMBL
      A0A178UXJ8
      Conserved Domains (3) summary
      PLN02603
      Location:1 → 567
      PLN02603; asparaginyl-tRNA synthetase
      cd00776
      Location:205 → 562
      AsxRS_core; Asx tRNA synthetase (AspRS/AsnRS) class II core domain. Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as ...
      cd04318
      Location:112 → 194
      EcAsnRS_like_N; EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O48593.3

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