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    meis3.S Meis homeobox 3 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 379219, updated on 4-Jan-2025

    Summary

    Official Symbol
    meis3.S
    Official Full Name
    Meis homeobox 3 S homeolog
    Primary source
    Xenbase:XB-GENE-485341
    Locus tag
    XELAEV_18042559mg
    See related
    EnsemblRapid:ENSXLAG00005009073 AllianceGenome:Xenbase:XB-GENE-485341
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    mrg2; meis3; XMeis3; meis3-a; meis3-b
    Summary
    Predicted to enable DNA binding activity. Predicted to act upstream of or within several processes, including anterior/posterior pattern specification; positive regulation of MAPK cascade; and positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. Orthologous to human MEIS3 (Meis homeobox 3). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

    See meis3.S in Genome Data Viewer
    Location:
    chromosome: 8S
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (85747148..85784104)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (83371981..83409093)

    Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene BRD4 interacting chromatin remodelling complex associated protein S homeolog Neighboring gene NSF attachment protein beta S homeolog Neighboring gene solute carrier family 8 member A2 S homeolog Neighboring gene uncharacterized LOC121397789 Neighboring gene proteasome 26S subunit, non-ATPase 8 S homeolog

    Genomic regions, transcripts, and products

    General gene information

    Clone Names

    • MGC52546, MGC130805

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within animal organ development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within anterior/posterior pattern specification ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within central nervous system development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within hindbrain development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within positive regulation of MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001086063.1NP_001079532.1  homeobox protein meis3-B

      See identical proteins and their annotated locations for NP_001079532.1

      Status: PROVISIONAL

      Source sequence(s)
      BC108488
      UniProtKB/Swiss-Prot
      Q2VPN5, Q7ZY13
      Related
      ENSXLAP00005026452.1, ENSXLAT00005027184.1
      Conserved Domains (2) summary
      pfam05920
      Location:285324
      Homeobox_KN; Homeobox KN domain
      pfam16493
      Location:102185
      Meis_PKNOX_N; N-terminal of Homeobox Meis and PKNOX1

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      85747148..85784104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018231837.2XP_018087326.1  homeobox protein meis3-B isoform X2

      UniProtKB/TrEMBL
      A0A1L8F3W8, A0A974H6M4
      Related
      ENSXLAP00005026397.1, ENSXLAT00005027129.1
    2. XM_018231836.2XP_018087325.1  homeobox protein meis3-B isoform X1

      UniProtKB/TrEMBL
      A0A1L8F3Y6, A0A974H671