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    ppa2.L pyrophosphatase (inorganic) 2 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 444459, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ppa2.L
    Official Full Name
    pyrophosphatase (inorganic) 2 L homeolog
    Primary source
    Xenbase:XB-GENE-961149
    Locus tag
    XELAEV_18034852mg
    See related
    EnsemblRapid:ENSXLAG00005029971 AllianceGenome:Xenbase:XB-GENE-961149
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    ppa2; ppa2.S
    Summary
    Predicted to enable inorganic diphosphate phosphatase activity and magnesium ion binding activity. Predicted to act upstream of or within phosphate-containing compound metabolic process. Predicted to be located in cytoplasm. Orthologous to human PPA2 (inorganic pyrophosphatase 2). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See ppa2.L in Genome Data Viewer
    Location:
    chromosome: 7L
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 7L NC_054383.1 (39088742..39133968, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 7L NC_030736.1 (36614872..36660276, complement)

    Chromosome 7L - NC_054383.1Genomic Context describing neighboring genes Neighboring gene trypsin like peroxisomal matrix peptidase 1 L homeolog Neighboring gene secretion associated, Ras related GTPase 1A L homeolog Neighboring gene neuropeptide FF receptor 1, gene 1 L homeolog Neighboring gene leucine rich repeat containing 20 L homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC83669

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inorganic diphosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphate-containing compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pyrophosphatase (inorganic) 2 L homeolog
    Names
    pyrophosphatase (inorganic) 2 S homeolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001092561.1 → NP_001086030.1  pyrophosphatase (inorganic) 2 L homeolog

      See identical proteins and their annotated locations for NP_001086030.1

      Status: PROVISIONAL

      Source sequence(s)
      BC073722
      UniProtKB/TrEMBL
      A0A974CEN2, Q6GN00
      Related
      ENSXLAP00005089740.1, ENSXLAT00005091415.1
      Conserved Domains (1) summary
      cl00217
      Location:2 → 241
      pyrophosphatase; Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers.

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054383.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      39088742..39133968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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