Ranbp6 RAN binding protein 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ranbp6provided by RGD
Official Full Name: RAN binding protein 6provided by RGD
Primary source: RGD:1305165
See related: EnsemblRapid:ENSRNOG00000053859 AllianceGenome:RGD:1305165
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Predicted to be located in mitochondrion. Predicted to be active in cytoplasm; nucleus; and synapse. Orthologous to human RANBP6 (RAN binding protein 6). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: 1q52

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (236985930..236990451, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (227572394..227576915, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (247980976..247985553, complement)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:237919 (e-PCR)
- UniSTS:237919

RH142891 (e-PCR)
- UniSTS:232138

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables nuclear import signal receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables nuclear localization sequence binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein import into nucleus	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in synapse	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: ran-binding protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001107584.1 → NP_001101054.1 ran-binding protein 6

See identical proteins and their annotated locations for NP_001101054.1

Status: PROVISIONAL

Source sequence(s)

CH473953

UniProtKB/TrEMBL

A6I0X4, D4A634

Related

ENSRNOP00000074790.2, ENSRNOT00000078998.3

Conserved Domains (5) summary

COG5215
Location:309 → 640

KAP95; Karyopherin (importin) beta [Intracellular trafficking and secretion]

sd00044
Location:330 → 353

HEAT; HEAT repeat [structural motif]

pfam18808
Location:284 → 365

Importin_rep_4; Importin repeat

pfam18816
Location:1013 → 1060

Importin_rep_5; Importin repeat

pfam18829
Location:773 → 882

Importin_rep_6; Importin repeat 6