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    CDPMEK 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817234, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDPMEK
    Official Full Name
    4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase
    Primary source
    TAIR:AT2G26930
    Locus tag
    AT2G26930
    See related
    Araport:AT2G26930
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    4-(cytidine 5'-diphospho)-2-C-methyl-d-erythritol kinase; 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase; 4-(CYTIDINE 5'-PHOSPHO)-2-C-METHYL-D-ERITHRITOL KINASE; 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL KINASE; ATCDPMEK; CMEK; CMK; F12C20.3; F12C20_3; ISPE; PDE277; PIGMENT DEFECTIVE 277
    Summary
    Encodes a 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase.
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    Genomic context

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    See CDPMEK in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Sequence:
    Chromosome: 2; NC_003071.7 (11491707..11494290, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Sodium Bile acid symporter family Neighboring gene pleiotropic drug resistance 4 Neighboring gene Ubiquitin-associated/translation elongation factor EF1B protein Neighboring gene C2H2-type zinc finger family protein Neighboring gene myb domain protein 104

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism. Lange BM, et al. Plant Mol Biol, 2003 Apr. PMID 12777052
    2. Redox Conformation-Specific Protein-Protein Interactions of the 2-Cysteine Peroxiredoxin in Arabidopsis. Liebthal M, et al. Antioxidants (Basel), 2020 Jun 11. PMID 32545358, Free PMC Article
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128250.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in terpenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase
    NP_180261.1
    • 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase (CDPMEK); FUNCTIONS IN: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity; INVOLVED IN: response to light stimulus; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (InterPro:IPR004424), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), GHMP kinase (InterPro:IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721), GHMP kinase, C-terminal (InterPro:IPR013750); Has 6617 Blast hits to 6617 proteins in 2226 species: Archae - 3; Bacteria - 4583; Metazoa - 0; Fungi - 2; Plants - 69; Viruses - 0; Other Eukaryotes - 1960 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11491707..11494290 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128250.4 → NP_180261.1  4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180261.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81014, Q9GI18
      UniProtKB/TrEMBL
      A0A178VZZ2, A0A5S9X1J0
      Conserved Domains (1) summary
      COG1947
      Location:70 → 329
      IspE; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Lipid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81014.1

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