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    SCC3 sister-chromatid cohesion protein 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819410, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SCC3
    Official Full Name
    sister-chromatid cohesion protein 3
    Primary source
    TAIR:AT2G47980
    Locus tag
    AT2G47980
    See related
    Araport:AT2G47980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSCC3; sister-chromatid cohesion protein 3; SISTER-CHROMATID COHESION PROTEIN 3; T9J23.3
    Summary
    Essential to the monopolar orientation of the kinetochores during meiosis.
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    Genomic context

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    See SCC3 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    21
    Sequence:
    Chromosome: 2; NC_003071.7 (19631207..19636978)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex subunit-like protein Neighboring gene Nuclear pore localization protein NPL4 Neighboring gene ncRNA Neighboring gene transducin family protein / WD-40 repeat family protein Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtREC8 and AtSCC3 are essential to the monopolar orientation of the kinetochores during meiosis. Chelysheva L, et al. J Cell Sci, 2005 Oct 15. PMID 16176934
    2. A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis. Waidmann S, et al. Plant Cell, 2014 Nov. PMID 25387881, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_130365.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within meiotic sister chromatid cohesion, centromeric IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within spindle attachment to meiosis I kinetochore IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    sister-chromatid cohesion protein 3
    NP_566119.1
    • sister-chromatid cohesion protein 3 (SCC3); FUNCTIONS IN: binding; INVOLVED IN: mitosis, attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation, meiotic sister chromatid cohesion, centromeric; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-type fold (InterPro:IPR016024), STAG (InterPro:IPR013721), Stromalin conservative domain (InterPro:IPR020839); Has 568 Blast hits to 559 proteins in 184 species: Archae - 0; Bacteria - 2; Metazoa - 324; Fungi - 134; Plants - 52; Viruses - 0; Other Eukaryotes - 56 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      19631207..19636978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130365.4 → NP_566119.1  sister-chromatid cohesion protein 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566119.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82265, Q8LFH0, Q9XGM9
      UniProtKB/TrEMBL
      A0A178VN21, A0A5S9X805
      Conserved Domains (1) summary
      pfam08514
      Location:143 → 247
      STAG; STAG domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82265.2

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