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    ML2 MEI2-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818890, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ML2
    Official Full Name
    MEI2-like 2
    Primary source
    TAIR:AT2G42890
    Locus tag
    AT2G42890
    See related
    Araport:AT2G42890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AML2; F7D19.11; F7D19_11; MEI2-like 2
    Summary
    A member of mei2-like gene family, predominantly plant-based family of genes encoding RNA binding proteins with characteristic presence of a highly conserved RNA binding motif first described in the mei2 gene of the fission yeast S. pombe. In silico analyses reveal nine mei2 -like genes in A. thaliana. They were grouped into four distinct clades, based on overall sequence similarity and subfamily-specific sequence elements. AML2 is a member of two sister clades of mei2-like gene family, AML1 through AML5, and belongs to the clade named ALM235. AML2 is expressed during early embryo development (heart and torpedo stage) and predominantly in vegetative organs; no significant accumulation was detected in floral apices.
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    Genomic context

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    See ML2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Sequence:
    Chromosome: 2; NC_003071.7 (17849819..17854553)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene MAP kinase 20 Neighboring gene Defensin-like (DEFL) family protein Neighboring gene Plant basic secretory protein (BSP) family protein Neighboring gene Phosphoribosyltransferase family protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis-mei2-like genes play a role in meiosis and vegetative growth in Arabidopsis. Kaur J, et al. Plant Cell, 2006 Mar. PMID 16473967, Free PMC Article
    2. PLASTOCHRON2 regulates leaf initiation and maturation in rice. Kawakatsu T, et al. Plant Cell, 2006 Mar. PMID 16461585, Free PMC Article
    3. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001084574.1
    NM_129850.4
    NM_201945.3

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    involved_in positive regulation of growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    MEI2-like 2
    NP_001078043.1
    • MEI2-like 2 (ML2); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 7605 Blast hits to 6029 proteins in 352 species: Archae - 6; Bacteria - 46; Metazoa - 4200; Fungi - 1128; Plants - 1425; Viruses - 0; Other Eukaryotes - 800 (source: NCBI BLink).
    NP_565990.1
    • MEI2-like 2 (ML2); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 7613 Blast hits to 6033 proteins in 353 species: Archae - 6; Bacteria - 46; Metazoa - 4198; Fungi - 1128; Plants - 1433; Viruses - 0; Other Eukaryotes - 802 (source: NCBI BLink).
    NP_973674.1
    • MEI2-like 2 (ML2); FUNCTIONS IN: RNA binding, nucleotide binding, nucleic acid binding; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA recognition motif, RNP-1 (InterPro:IPR000504), RNA recognition motif 2 (InterPro:IPR007201), Nucleotide-binding, alpha-beta plait (InterPro:IPR012677); BEST Arabidopsis thaliana protein match is: MEI2-like protein 5 (TAIR:AT1G29400.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17849819..17854553
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129850.4 → NP_565990.1  MEI2-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565990.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8S8G0, Q9ASS1, Q9SEU3, Q9SJG8
      UniProtKB/TrEMBL
      A0A178VQK0, A0A5S9X6K0
      Conserved Domains (4) summary
      pfam04059
      Location:679 → 775
      RRM_2; RNA recognition motif 2
      TIGR01628
      Location:149 → 471
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12524
      Location:197 → 273
      RRM1_MEI2_like; RNA recognition motif 1 (RRM1) found in plant Mei2-like proteins
      cd12529
      Location:282 → 352
      RRM2_MEI2_like; RNA recognition motif 2 (RRM2) found in plant Mei2-like proteins

    2. NM_001084574.1 → NP_001078043.1  MEI2-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001078043.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654F2L7, F4IP94
      Conserved Domains (4) summary
      pfam04059
      Location:666 → 762
      RRM_2; RNA recognition motif 2
      TIGR01628
      Location:136 → 458
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12524
      Location:184 → 260
      RRM1_MEI2_like; RNA recognition motif 1 (RRM1) found in plant Mei2-like proteins
      cd12529
      Location:269 → 339
      RRM2_MEI2_like; RNA recognition motif 2 (RRM2) found in plant Mei2-like proteins

    3. NM_201945.3 → NP_973674.1  MEI2-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973674.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654F2L7, F4IP94
      Conserved Domains (4) summary
      pfam04059
      Location:666 → 762
      RRM_2; RNA recognition motif 2
      TIGR01628
      Location:136 → 458
      PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
      cd12524
      Location:184 → 260
      RRM1_MEI2_like; RNA recognition motif 1 (RRM1) found in plant Mei2-like proteins
      cd12529
      Location:269 → 339
      RRM2_MEI2_like; RNA recognition motif 2 (RRM2) found in plant Mei2-like proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SJG8.2

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