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    XERICO RING/U-box superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 814962, updated on 18-Sep-2024

    Summary

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    Official Symbol
    XERICO
    Official Full Name
    RING/U-box superfamily protein
    Primary source
    TAIR:AT2G04240
    Locus tag
    AT2G04240
    See related
    Araport:AT2G04240
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Summary
    Encodes a small protein with an N-terminal trans-membrane domain and a RING-H2 zinc finger motif located at the C-terminus. Gene expression is induced by salt and osmotic stress. Transcrips levels are induced by DELLA proteins and repressed by gibberellic acid. Involved in ABA metabolism.
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    Genomic context

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    See XERICO in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Sequence:
    Chromosome: 2; NC_003071.7 (1461548..1462944, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene FBD, F-box and Leucine Rich Repeat domains containing protein Neighboring gene uncharacterized protein Neighboring gene miscRNA Neighboring gene miscRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Upregulation of an Arabidopsis RING-H2 gene, XERICO, confers drought tolerance through increased abscisic acid biosynthesis. Ko JH, et al. Plant J, 2006 Aug. PMID 16792696
    2. Global analysis of della direct targets in early gibberellin signaling in Arabidopsis. Zentella R, et al. Plant Cell, 2007 Oct. PMID 17933900, Free PMC Article
    3. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
    4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The XERICO gene is involved in drought tolerance through regulation of ABA synthesis. [XERICO]
      Title: Upregulation of an Arabidopsis RING-H2 gene, XERICO, confers drought tolerance through increased abscisic acid biosynthesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_126459.3
    NM_201687.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within abscisic acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to gibberellin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    RING/U-box superfamily protein
    NP_178507.1
    • XERICO; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: brassinosteroid-responsive RING-H2 (TAIR:AT3G61460.1); Has 7967 Blast hits to 7952 proteins in 266 species: Archae - 0; Bacteria - 0; Metazoa - 1949; Fungi - 661; Plants - 4072; Viruses - 19; Other Eukaryotes - 1266 (source: NCBI BLink).
    NP_973416.1
    • XERICO; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: brassinosteroid-responsive RING-H2 (TAIR:AT3G61460.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      1461548..1462944 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_126459.3 → NP_178507.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178507.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SI09
      UniProtKB/TrEMBL
      A0A178VXZ4, A0A654F2P6
      Conserved Domains (2) summary
      cd00162
      Location:103 → 144
      RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
      cl17238
      Location:103 → 148
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain

    2. NM_201687.1 → NP_973416.1  RING/U-box superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973416.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9SI09
      UniProtKB/TrEMBL
      A0A178VXZ4, A0A654F2P6
      Conserved Domains (2) summary
      cd00162
      Location:103 → 144
      RING_Ubox; RING-H2 finger (C3H2C3-type) [structural motif]
      cl17238
      Location:103 → 148
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SI09.1

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