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    EDA10 SEC7-like guanine nucleotide exchange family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839301, updated on 18-Sep-2024

    Summary

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    Official Symbol
    EDA10
    Official Full Name
    SEC7-like guanine nucleotide exchange family protein
    Primary source
    TAIR:AT1G01960
    Locus tag
    AT1G01960
    See related
    Araport:AT1G01960
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    embryo sac development arrest 10; F22M8.9; F22M8_9
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    Genomic context

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    See EDA10 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    11
    Sequence:
    Chromosome: 1; NC_003070.9 (330588..337912, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene SET domain-containing protein Neighboring gene zinc finger protein-like protein Neighboring gene Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene armadillo repeat kinesin 2 Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene FAD-binding Berberine family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Delivery of endocytosed proteins to the cell-division plane requires change of pathway from recycling to secretion. Richter S, et al. Elife, 2014 Apr 8. PMID 24714496, Free PMC Article
    2. Involvement of BIG5 and BIG3 in BRI1 Trafficking Reveals Diverse Functions of BIG-subfamily ARF-GEFs in Plant Growth and Gravitropism. Xue S, et al. Int J Mol Sci, 2019 May 11. PMID 31083521, Free PMC Article
    3. Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis. Pagnussat GC, et al. Development, 2005 Feb. PMID 15634699
    4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. BIG5 functions redundantly with BIG3 in plant growth and gravitropism, and BIG5 participates in Brassinosteroid signal transduction pathway through regulating BRI1 trafficking.[BIG3]
      Title: Involvement of BIG5 and BIG3 in BRI1 Trafficking Reveals Diverse Functions of BIG-subfamily ARF-GEFs in Plant Growth and Gravitropism.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_100076.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within megagametogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of ARF protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in trans-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SEC7-like guanine nucleotide exchange family protein
    NP_171698.1
    • embryo sac development arrest 10 (EDA10); FUNCTIONS IN: binding, ARF guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity; INVOLVED IN: megagametogenesis; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SEC7-like (InterPro:IPR000904), Armadillo-type fold (InterPro:IPR016024), Protein of unknown function DUF1981, SEC7 associated (InterPro:IPR015403); BEST Arabidopsis thaliana protein match is: SEC7-like guanine nucleotide exchange family protein (TAIR:AT3G60860.1); Has 2904 Blast hits to 2648 proteins in 246 species: Archae - 0; Bacteria - 34; Metazoa - 1480; Fungi - 646; Plants - 300; Viruses - 0; Other Eukaryotes - 444 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      330588..337912 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100076.3 → NP_171698.1  SEC7-like guanine nucleotide exchange family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_171698.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LPC5
      UniProtKB/TrEMBL
      A0A178WBT3, A0A5S9S5T0, A0A654E6E9, A0A7G2DRR7
      Conserved Domains (1) summary
      PLN03076
      Location:1 → 1749
      PLN03076; ARF guanine nucleotide exchange factor (ARF-GEF); Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LPC5.1

    Gene LinkOut

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