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    HNH endonuclease domain-containing protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838449, updated on 18-Sep-2024

    Summary

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    Official Full Name
    HNH endonuclease domain-containing protein
    Primary source
    TAIR:AT1G18680
    Locus tag
    AT1G18680
    See related
    Araport:AT1G18680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6A14.21; F6A14_21
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (6431938..6433552, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene plasmodesmata callose-binding protein 3 Neighboring gene zinc finger (C3HC4-type RING finger) family protein Neighboring gene Protein kinase superfamily protein Neighboring gene Galactosyl transferase GMA12/MNN10 family protein Neighboring gene DNAJ heat shock N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Mitochondrial Endonuclease M20 Participates in the Down-Regulation of Mitochondrial DNA in Pollen Cells. Ma F, et al. Plant Physiol, 2018 Dec. PMID 30301773, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. At1g18680 (AtM20) participation in the reduction of mitochondrial DNA levels in pollen cells.
      Title: The Mitochondrial Endonuclease M20 Participates in the Down-Regulation of Mitochondrial DNA in Pollen Cells.
    Submit: New GeneRIF Correction

    General gene information

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    NM_101726.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables endonuclease activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial DNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    HNH endonuclease domain-containing protein
    NP_173303.1
    • HNH endonuclease domain-containing protein; FUNCTIONS IN: endonuclease activity, nucleic acid binding; INVOLVED IN: N-terminal protein myristoylation; LOCATED IN: chloroplast; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: HNH nuclease (InterPro:IPR003615), HNH endonuclease (InterPro:IPR002711); BEST Arabidopsis thaliana protein match is: HNH endonuclease (TAIR:AT3G47490.1); Has 84 Blast hits to 84 proteins in 23 species: Archae - 0; Bacteria - 8; Metazoa - 0; Fungi - 0; Plants - 68; Viruses - 0; Other Eukaryotes - 8 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6431938..6433552 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101726.4 → NP_173303.1  HNH endonuclease domain-containing protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173303.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WFA8, A0A7G2DRJ9, Q9M9T9
      Conserved Domains (1) summary
      cd00085
      Location:77 → 116
      HNHc; HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and ...
    Nucleotide Protein
    Heading Accession and Version

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