ROP2 RHO-related protein from plants 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ROP2
Official Full Name: RHO-related protein from plants 2
Primary source: TAIR:AT1G20090
Locus tag: AT1G20090
See related: Araport:AT1G20090
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: Arabidopsis RAC-like 4; ARAC4; ATRAC4; ATROP2; GTP-BINDING PROTEIN ARAC4; RHO-related protein from plants 2; T20H2.12; T20H2_12
Summary: Member of the Rho GTPase family. Functions to organize the microtubular cytoskeleton in combination with RIC1 and RIC4. These interactions affect pavement cell morphogenesis and pollen tube growth. ROP2 expression is stimulated by brassinosteroid treatment. Inhibit light-induced stomatal opening.
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Genomic context

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See ROP2 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 7

Sequence:: Chromosome: 1; NC_003070.9 (6966842..6969009)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

AXR1 modulates trichome morphogenesis through mediating ROP2 stability in Arabidopsis.
Title: AXR1 modulates trichome morphogenesis through mediating ROP2 stability in Arabidopsis.
Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis.
Title: Diverse nitrogen signals activate convergent ROP2-TOR signaling in Arabidopsis.
data suggest that AtrbohD functions downstream of ROP2 to positively regulate the response to waterlogging stress in Arabidopsis.
Title: AtrbohD functions downstream of ROP2 and positively regulates waterlogging response in Arabidopsis.
Results indicate a function of MICROTUBULE-ASSOCIATED PROTEIN18 (MAP18) in the regulation of Rop GTPase ROP2 (ROP2) activation during root hair growth.
Title: The Microtubule-Associated Protein MAP18 Affects ROP2 GTPase Activity during Root Hair Growth.
we reveal that the small GTPase Rho-related protein 2 (ROP2) transduces light-auxin signal to activate TOR by direct interaction, which, in turn, promotes transcription factors E2Fa,b for activating cell cycle genes in shoot apexes. Consistently, constitutively activated ROP2 plants stimulate TOR in the shoot apex and cause true leaf development even without light.
Title: Differential TOR activation and cell proliferation in Arabidopsis root and shoot apexes.
ROP2 is required for the formation of a fine endoplasmic reticulum structure in the subapical zone of growing root hairs.
Title: A GTPase-Dependent Fine ER Is Required for Localized Secretion in Polarized Growth of Root Hairs1.
RopGEF2 interacted with ROP7 and ROP2 and enhanced their intrinsic nucleotide exchange rates.Rop2 plays a role in the red lignt-induced stomatal opening.
Title: The RopGEF2-ROP7/ROP2 Pathway Activated by phyB Suppresses Red Light-Induced Stomatal Opening.
ROP2-RIC1 pathway fine-tunes microtubule dynamics in response to salt stress in Arabidopsis.ROP2 participates in salt tolerance through suppressing RIC1.
Title: A ROP2-RIC1 pathway fine-tunes microtubule reorganization for salt tolerance in Arabidopsis.
Results suggest that during the late petal development stages, SPIKE1 (SPK1), encoding a guanine nucleotide exchange factor and Rho of Plants (ROP) GTPase proteins (ROP2, ROP4, and ROP6)-dependent signaling module influences anisotropic growth in the petal and defines the final organ shape.
Title: SPIKE1 Activates ROP GTPase to Modulate Petal Growth and Shape.
Here, the authors report that the small GTPase ROP2, if activated by the phytohormone auxin, promotes activation of TOR, and thus translation reinitiation of uORF-containing mRNAs.
Title: GTPase ROP2 binds and promotes activation of target of rapamycin, TOR, in response to auxin.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_101863.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables GTP binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within_negative_effect anisotropic cell growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cell morphogenesis	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within cortical microtubule organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within microtubule cytoskeleton organization	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within petal morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within pollen tube growth	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of stomatal movement	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to light stimulus	IDA Inferred from Direct Assay more info	PubMed
involved_in root hair elongation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in root hair initiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in small GTPase-mediated signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	HDA more info	PubMed
located_in nucleolus	HDA more info	PubMed
located_in nucleus	HDA more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: RHO-related protein from plants 2

NP_173437.1

RHO-related protein from plants 2 (ROP2); CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), Ras GTPase (InterPro:IPR001806), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Ras small GTPase, Ras type (InterPro:IPR003577), Small GTPase, Rho type (InterPro:IPR003578); BEST Arabidopsis thaliana protein match is: RAC-like GTP binding protein 5 (TAIR:AT1G75840.1); Has 24645 Blast hits to 24619 proteins in 682 species: Archae - 9; Bacteria - 67; Metazoa - 12700; Fungi - 3846; Plants - 2697; Viruses - 20; Other Eukaryotes - 5306 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

6966842..6969009

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_101863.4 → NP_173437.1 RHO-related protein from plants 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_173437.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q38919

UniProtKB/TrEMBL

A0A178WNE1, A0A384L636, Q0WU07

Conserved Domains (1) summary

cd04133
Location:5 → 177

Rop_like; Rho-related protein from plants (Rop)-like