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    ATTRX4 Thioredoxin superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838562, updated on 18-Sep-2024

    Summary

    Official Symbol
    ATTRX4
    Official Full Name
    Thioredoxin superfamily protein
    Primary source
    TAIR:AT1G19730
    Locus tag
    AT1G19730
    See related
    Araport:AT1G19730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATH4; F14P1.32; F14P1_32; THIOREDOXIN; thioredoxin H-type 4
    Summary
    encodes a cytosolic thioredoxin that reduces disulfide bridges of target proteins by the reversible formation of a disulfide bridge between two neighboring Cys residues present in the active site. Thioredoxins have been found to regulate a variety of biological reactions in prokaryotic and eukaryotic cells.
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    Genomic context

    See ATTRX4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (6822847..6824071, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene Mannose-binding lectin superfamily protein Neighboring gene Pentatricopeptide repeat (PPR-like) superfamily protein Neighboring gene ATP-dependent protease La (LON) domain protein Neighboring gene Transducin/WD40 repeat-like superfamily protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    Thioredoxin superfamily protein
    NP_173403.1
    • ATTRX4; FUNCTIONS IN: oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; INVOLVED IN: cell redox homeostasis; LOCATED IN: cytosol; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin, core (InterPro:IPR015467), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: thioredoxin H-type 5 (TAIR:AT1G45145.1); Has 19449 Blast hits to 19098 proteins in 2963 species: Archae - 279; Bacteria - 10803; Metazoa - 1859; Fungi - 973; Plants - 1850; Viruses - 7; Other Eukaryotes - 3678 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6822847..6824071 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101829.4NP_173403.1  Thioredoxin superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173403.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q38880, Q39239, Q541W4, Q8L907, Q9FXH2
      UniProtKB/TrEMBL
      A0A5S9V6S4, A0A654EM45
      Conserved Domains (1) summary
      cd02947
      Location:20110
      TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...