ABCG25 ATP-binding cassette family G25 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: ABCG25
Official Full Name: ATP-binding cassette family G25
Primary source: TAIR:AT1G71960
Locus tag: AT1G71960
See related: Araport:AT1G71960
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA ATP-BINDING CASETTE FAMILY G 25; Arabidopsis thaliana ATP-binding cassette G25; ATABCG25; ATP-binding casette family G25; ATP-binding casette G25; F17M19.11; F17M19_11
Summary: Encodes a plasma membrane localized ABC transporter involved in abscisic acid transport and responses.
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Genomic context

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See ABCG25 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 4

Sequence:: Chromosome: 1; NC_003070.9 (27082394..27088248, complement)

Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Endomembrane-biased dimerization of ABCG16 and ABCG25 transporters determines their substrate selectivity in ABA-regulated plant growth and stress responses.
Title: Endomembrane-biased dimerization of ABCG16 and ABCG25 transporters determines their substrate selectivity in ABA-regulated plant growth and stress responses.
Structural basis for abscisic acid efflux mediated by ABCG25 in Arabidopsis thaliana.
Title: Structural basis for abscisic acid efflux mediated by ABCG25 in Arabidopsis thaliana.
Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.
Title: Cryo-EM structure and molecular mechanism of abscisic acid transporter ABCG25.
Brachypodium BdABCG25 is a homolog of Arabidopsis AtABCG25 involved in the transport of abscisic acid.
Title: Brachypodium BdABCG25 is a homolog of Arabidopsis AtABCG25 involved in the transport of abscisic acid.
Data propose that the spatial regulation of ABCG25 is an important component of the mechanism by which plants fine-tune cellular ABA levels according to cellular and environmental conditions
Title: Spatial Regulation of ABCG25, an ABA Exporter, Is an Important Component of the Mechanism Controlling Cellular ABA Levels.
AtABCG25 overexpression enhances drought tolerance.
Title: Overexpression of AtABCG25 enhances the abscisic acid signal in guard cells and improves plant water use efficiency.
ABCG25 exports abscisic acid from the endosperm, regulating seed germination.
Title: Abscisic acid transporters cooperate to control seed germination.
AtABCG25, encodes a protein that is responsible for ABA transport and responses in Arabidopsis. [ABCG25]
Title: ABC transporter AtABCG25 is involved in abscisic acid transport and responses.

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General gene information

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NM_105854.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables ABC-type transporter activity	IEA Inferred from Electronic Annotation more info
enables ATP hydrolysis activity	IEA Inferred from Electronic Annotation more info
enables ATPase-coupled transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables ATPase-coupled transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables ATPase-coupled transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables efflux transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables efflux transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within abscisic acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in abscisic acid transport	IDA Inferred from Direct Assay more info	PubMed
involved_in abscisic acid-activated signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in abscisic acid-activated signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in export from cell	IDA Inferred from Direct Assay more info	PubMed
involved_in export from cell	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intercellular transport	IDA Inferred from Direct Assay more info	PubMed
involved_in intercellular transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of post-embryonic development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to abscisic acid	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to abscisic acid	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to cold	IEP Inferred from Expression Pattern more info	PubMed
involved_in response to heat	IEP Inferred from Expression Pattern more info	PubMed
involved_in transmembrane transport	IDA Inferred from Direct Assay more info	PubMed
involved_in transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: ATP-binding cassette family G25

NP_565030.1

ATP-binding casette family G25 (ABCG25); CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC-2 type transporter (InterPro:IPR013525); BEST Arabidopsis thaliana protein match is: ATP-binding cassette 14 (TAIR:AT1G31770.1); Has 400795 Blast hits to 363827 proteins in 4147 species: Archae - 6947; Bacteria - 316897; Metazoa - 8938; Fungi - 6866; Plants - 5594; Viruses - 13; Other Eukaryotes - 55540 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003070.9 Reference assembly

Range

27082394..27088248 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_105854.1 → NP_565030.1 ATP-binding cassette family G25 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_565030.1

Status: REVIEWED

UniProtKB/Swiss-Prot

C0Z3C6, Q84TH5, Q949Y4, Q9C8W6

UniProtKB/TrEMBL

A0A7G2E583

Conserved Domains (3) summary

cd03213
Location:70 → 290

ABCG_EPDR; Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily

PLN03211
Location:1 → 662

PLN03211; ABC transporter G-25; Provisional

pfam01061
Location:393 → 592

ABC2_membrane; ABC-2 type transporter