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    Disease resistance protein (CC-NBS-LRR class) family [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837783, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Disease resistance protein (CC-NBS-LRR class) family
    Primary source
    TAIR:AT1G12290
    Locus tag
    AT1G12290
    See related
    Araport:AT1G12290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5O11.3; F5O11_3
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (4177917..4182593, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene stress-inducible protein Neighboring gene LRR and NB-ARC domains-containing disease resistance protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene ncRNA Neighboring gene ankyrin repeat/KH domain protein (DUF1442) Neighboring gene Calcium-binding EF-hand family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure and function analysis of a CC-NBS-LRR protein AT1G12290. Huang J, et al. Biochem Biophys Res Commun, 2021 Jan 1. PMID 33272575
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Structure and function analysis of a CC-NBS-LRR protein AT1G12290.
      Title: Structure and function analysis of a CC-NBS-LRR protein AT1G12290.
    Submit: New GeneRIF Correction

    General gene information

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    NM_001332028.1
    NM_001332029.1
    NM_001332030.1
    NM_101101.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ADP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of programmed cell death IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Disease resistance protein (CC-NBS-LRR class) family
    NP_001318986.1
    • Disease resistance protein (CC-NBS-LRR class) family; FUNCTIONS IN: ATP binding; INVOLVED IN: N-terminal protein myristoylation, defense response; EXPRESSED IN: stem, inflorescence meristem, root, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (CC-NBS-LRR class) family (TAIR:AT1G12220.2); Has 2708 Blast hits to 2465 proteins in 164 species: Archae - 0; Bacteria - 155; Metazoa - 197; Fungi - 19; Plants - 2299; Viruses - 0; Other Eukaryotes - 38 (source: NCBI BLink).
    NP_172693.1
    • Disease resistance protein (CC-NBS-LRR class) family; FUNCTIONS IN: ATP binding; INVOLVED IN: N-terminal protein myristoylation, defense response; EXPRESSED IN: stem, inflorescence meristem, root, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: NB-ARC (InterPro:IPR002182), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (CC-NBS-LRR class) family (TAIR:AT1G12220.2); Has 16903 Blast hits to 15496 proteins in 648 species: Archae - 22; Bacteria - 963; Metazoa - 2036; Fungi - 239; Plants - 13383; Viruses - 4; Other Eukaryotes - 256 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      4177917..4182593 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001332028.1 → NP_001318986.1  Disease resistance protein (CC-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W4C1, F4IC69

    2. NM_001332029.1 → NP_001320959.1  Disease resistance protein (CC-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W4C1, F4IC69

    3. NM_101101.5 → NP_172693.1  Disease resistance protein (CC-NBS-LRR class) family [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172693.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P60839, Q9LNB5
      UniProtKB/TrEMBL
      A0A178W4C1
      Conserved Domains (3) summary
      sd00031
      Location:542 → 566
      LRR_1; leucine-rich repeat [structural motif]
      pfam00931
      Location:159 → 438
      NB-ARC; NB-ARC domain
      pfam13855
      Location:540 → 601
      LRR_8; Leucine rich repeat

    4. NM_001332030.1 → NP_001320960.1  Disease resistance protein (CC-NBS-LRR class) family [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178W4C1, F4IC69
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P60839.1

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