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    PAL4 phenylalanine ammonia-lyase 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820196, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAL4
    Official Full Name
    phenylalanine ammonia-lyase 4
    Primary source
    TAIR:AT3G10340
    Locus tag
    AT3G10340
    See related
    Araport:AT3G10340
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    phenylalanine ammonia-lyase 4
    Summary
    Encodes PAL4, a putative a phenylalanine ammonia-lyase. Arabidopsis has four PALs: AT2G37040 (PAL1), AT3G53260 (PAL2), AT5G04230 (PAL3) and AT3G10340 (PAL4).
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    Genomic context

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    See PAL4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    3
    Sequence:
    Chromosome: 3; NC_003074.8 (3203988..3208135)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Glycosyltransferase family 61 protein Neighboring gene Cyclin-like family protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene pumilio 4 Neighboring gene FAD-dependent oxidoreductase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis Kelch repeat F-box proteins regulate phenylpropanoid biosynthesis via controlling the turnover of phenylalanine ammonia-lyase. Zhang X, et al. Plant Cell, 2013 Dec. PMID 24363316, Free PMC Article
    2. Down-regulation of Kelch domain-containing F-box protein in Arabidopsis enhances the production of (poly)phenols and tolerance to ultraviolet radiation. Zhang X, et al. Plant Physiol, 2015 Feb. PMID 25502410, Free PMC Article
    3. Tandem affinity purification and mass spectrometric analysis of ubiquitylated proteins in Arabidopsis. Saracco SA, et al. Plant J, 2009 Jul. PMID 19292762, Free PMC Article
    4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • At3g10340_Arabidopsis_lyrata_ssp._lyrata_CAN1 (e-PCR)
    • At3g10340_Arabidopsis_lyrata_ssp._petraea_GER1 (e-PCR)
    NM_111869.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phenylalanine ammonia-lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cinnamic acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    phenylalanine ammonia-lyase 4
    NP_187645.1
    • phenylalanine ammonia-lyase 4 (PAL4); FUNCTIONS IN: ammonia-lyase activity, catalytic activity; INVOLVED IN: L-phenylalanine catabolic process, biosynthetic process; LOCATED IN: cytoplasm; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 4 anthesis, C globular stage, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Phenylalanine/histidine ammonia-lyase (InterPro:IPR001106), Phenylalanine/histidine ammonia-lyases, active site (InterPro:IPR022313), L-Aspartase-like (InterPro:IPR008948), Phenylalanine ammonia-lyase (InterPro:IPR005922); BEST Arabidopsis thaliana protein match is: PHE ammonia lyase 1 (TAIR:AT2G37040.1); Has 4898 Blast hits to 4876 proteins in 1415 species: Archae - 40; Bacteria - 2975; Metazoa - 80; Fungi - 127; Plants - 1177; Viruses - 0; Other Eukaryotes - 499 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3203988..3208135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111869.4 → NP_187645.1  phenylalanine ammonia-lyase 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187645.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q53ZM8, Q9SS45
      UniProtKB/TrEMBL
      A0A178V872, A0A654F5U4
      Conserved Domains (1) summary
      PLN02457
      Location:5 → 707
      PLN02457; phenylalanine ammonia-lyase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SS45.1

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